Bacterial Infection Flashcards

1
Q

Common gram + cocci

A

staphylococci
streptococci
enterococci

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2
Q

less common gram + rods

A

Diphtheria, Listeriosis, Anthrax, Nocardiosis

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3
Q

Infections brought about by staphylococcus

A

Abscess, sepsis, osteomyelitis, pneumonia, endocarditis, food poisoning, tss

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4
Q

Coagulase negative staph

A

S. epidermidis, S. saprophyticus

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5
Q

UTInin woman

A

S. saprophyticus

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6
Q

opportunistic, catheter

A

S.epidermidis

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7
Q

Clumping factor, binding to host endothelial cells

A

fibrinogen (fibronectin, vitronectin)

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8
Q

Attachment to artificial materials

A

Polysaccharide capsule

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9
Q

Binds fc portion

A

Surface protein A

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10
Q

holds the epidermal cells tightly together

A

Desmoglein 1 (cleaved by serine proteases Exfoliative a and b)

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11
Q

Assoc, with the use of hyperabsorbent tampons

A

TSS

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12
Q

Focal suppurative inflammation

A

furubcle or boil

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13
Q

deeper suppurative infection

A

carbuncle

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14
Q

Chronic suppurative infection of apocrine

glands, most often in the axilla

A

hidradenitis

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15
Q

Ritter disease, desquamation, sunburn like

A

Scalded Skin syndrome

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16
Q

Streptococcal (SOLH)

A

Skin, oropharynx, lungs, heart valves

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17
Q

Group A strep

A

S. pyogenes

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18
Q

strep grp b

A

s. agalactiae

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19
Q

Pathogenesis of s pyogenes

A

M protein, phage-encided pyrogenic exotoxin

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20
Q

Produces preumolysin

A

S. Pneumonia

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21
Q

Marked by edema, epiglottic swelling,
and punctuate abscesses of the tonsillar
crypts, sometimes accompanied by
cervical lymphadenopathy

A

strep pharnygitis

22
Q

important cause of lobar pneumonia

A

s. pneumoniae

23
Q

Produces a phage-encoded A-B toxin

that blocks host cell protein synthesis.

A

c. diphtheriae

24
Q

Outbreaks of are associated with contaminated
dairy products or processed fruits and
vegetables.

A

Lesteriosis

25
Q

In neonates and immunosuppressed adults, it can cause disseminated disease (granulomatosis infatiseptica of the newborn) and an exudative meningitis.

A

listeria monocytogenes

26
Q

The L. monocyotogenes escape from the phagolysosome

using a pore-forming protein,________, and two phospholipases.

A

listeriolysin O

27
Q

form of anthrax- Makes up 95% of naturally occurring
infections, begins as a painless, pruritic
papule that develops into a vesicle within
2 days.

A

cutaneous anthrax

28
Q

Causes hemorrhagic mediastinitis

A

inhalational anthrax

29
Q

rapidly leads to shock and frequently death within 1 to 2 days.

A

inhalational anthrax

30
Q

Produces potent toxin and an antiphagocytic

polyglutamyl capsule

A

B. anthrax

31
Q

Anthrax diagnosis: The presence of large_________ In chains, seen histopathologically using the Brown and Brenn stain or grown in culture suggests, the diagnosis.

A

boxcar shaped gram-positive extracellular bacteria

32
Q

are aerobic gram positive bacteria

found in soil that cause opportunistic infections.

A

nocardia

33
Q

manifests as an indolent illness with fever, weight
loss and cough which may be mistaken for
tuberculosis or malignancy.

A

respi infections with nocardia

34
Q
Nocardia  spp  stain  with  modified  acid-
fast  stains  ( )
A

Fite-Faraco stain

35
Q

are gram-negative diplococci that are flattened on the adjoining sides, giving
the pair the shape of coffee bean.

A

Neisserial spp.

36
Q

Neisserial spp have stringent nutritional

requirements and grow best on

A

enriched media

such as lysed sheep’s blood (chocolate) agar

37
Q

Disseminated infection of adults and adolescents
usually causes septic arthritis accompanied by a
rash of hemorrhagic papules and pustules.

A

gonorrhea

38
Q

Virulence factors of Bordetella pertussis include

A

pertussis toxin, adenylate cyclase toxin, dermonecrotic toxin and tracheal cytotoxin.

39
Q

ADP-ribosylates and inactivates
guanine nucleotide binding proteins so
these G pretties can no longer transduce
signals.

A

A unit

40
Q

contains four subunits
that bind to extracellular molecules and
allow the A subunits to enter cells.

A

B component

41
Q

hypercellularity and enlargement of the
mucosal lymph follicles and peribronchial lymph
nodes.

A

bordetella

42
Q

an opportunistic
aerobic gram-negative bacillus that is frequent, deadly pathogen in ppl with cystic fibrosis, severe burns, or neutropenia.

A

P. aeruginosa

43
Q

also causes corneal keratitis in wearers of contact
lenses, endocarditis, and osteomyelitis in
intravenous drug abusers, external otitis
(swimmer’s ear) in healthy individuals, and
severe external otitis in people with diabetes.

A

P. aeruginosa

44
Q

Pseudomonas spp. Cause necrotizing
pneumonia that is distributed through the
terminal airways in _____pattern

A

fleur-de-lis

45
Q

Gram-negative facultative intracellular bacterium
that causes an invasive, frequently fatal, infection
called plague

A

Y. pestis

46
Q

ileitis

A

Y. entercolitica

47
Q

mesenteric lyphadenitis

A

Y. pseudotuberculosis

48
Q

Severe, confluent, hemorrhagic and necrotizing
infections difficult to treat
bronchopneumonia, often with fibrinous pleuritis.

A

pneumonic plague

49
Q

Haemophilus ducreyi

A

Chancroid

50
Q

t or f
In contrast to the primary chancre of syphilis, the
ulcer of chancroid is not indurated, and multiple
lesions may be present

A

t