Bacteria Flashcards
gram ____ has a lipoprotein outer wall
negative
the cell wall of bacertai contains _______, which prevents osmotic lysis
proteoglycan
inhibiting the synthesis of peptidoglycan is one mechanism of action for ________
antimicrobials
so bacteria are also ______ with a polysaccharide coating which prevents phagocytosis
encapsulated
transpeptidase catalyzes the formation of the _____
cell wall
penicillin binds to _______ to inhibit it
transpeptidase
mycobacteria (TB), spirochetes, and mycoplasma are exceptions to _____ _____
gram stain
in gram ________, the peptidoglycan layer does not block diffusion of LMW compounds, so substances that damage the cytopasmic membrane can pass through
positive
in gram _____, the outer lipopolysaccharide membrane blocks the passage of substances to the peptidoglycan layer
negative
antibiotics and chemicals that attack the peptidoglycan wall are unable to pass through in _____ ______
gram negative
grape like cluster is _________
staphylococci
staphylococcus is the _____, whereas staphylococcus auras is the ________
genus
species
hydrogen peroxide is broken down by _______ and _______
catalase and peroxidase
coagulase activates ______, causing blood to clot
prothrombin
obligate aerobes cannot live without _____. they have catalase, peroxides, and superoxide dismutase
oxygen
facultative _____ can grow in air or under low oxygen tension
aerobes
______ aerobes have the faculties to be anaerobes but prefer aerobic conditions
facultative
obligate _______ are killed by oxygen. They have no enzymes to protect them
anaerobes
microaerophilic bacteria use _________ and have no ETC. they have tolerate low levels of oxygen. They don’t have catalase.
fermentation
________ infect deep tissues and are often associated with gas production
anaerobes
flagella is for mobility, _____ are for adhesion/binding, and capsules are for ______ from phagocytosis
pili
protection
endospores have _______ and are resistant to the environment
dormancy
_________ is the body’s solution to encapsulation
opsonization
facultative intracellular organisms are _______ by the host’s macrophages but they ______ within the WBC by inhibiting phagosome-lysosome fusion. They escape the host’s _______ peroxide and superoxide radicals
phagocytized
survive
exotoxins are _____ released from both gram ______ and gram negative bacteria
proteins
positive
almost all gram _____ have _____ (except listeria)
positive
exotoxins
enterotoxins are infectious ______ or food poisoning. Bacteria bind to the ____ _____
diarrhea
GI tract
In food poisoning, bacteria grow in the food and release ________ in the food. This results in diarrhea and vomiting for less tha ______ hours
enterotoxin
24 hrs
botulism and tetanus release ________
neurotoxins
pyogenic exotoxins stimulate the release of ________ and cause rash, fever, toxic shock syndrome (staph aureus and strep progenies)
cytokines
endotoxins are lipopolysaccharides within gram ______ outer membrane released with the death of the bacterium
negative
endotoxins are only in ______ ______
gram negative
endotoxins are not a _______ excreted like exotoxin, but a normal part of the _____ _____
protein
outer membrane
bacteremia can lead to ______, which causes a systemic immune response
sepsis
in septic shock, both gram ______ and gram ______ infection
positive and negative
________ are part of the outer membrane of gram negative bacteria and are ________when the bacteria die and the cell wall breaks apart
endotoxins
liberated
_______ are produced in _____ ______ and are released following lysis
exotoxins
gram positive
DNA fragments from one bacterium can incorporate itself into another _______
bacterium
a virus can infect a bacteria in ________, making it a bacteriophage
transduction
a bacteriophage carries a piece of bacterial ______ from one bacterium to another
DNA
in ______, DNA is transferred via cell to cell contact
conjugation
transposons have ______ and carry genes for antibiotic resistance and virulence
legs
__________ are gram positive spheres (cocci). They differentiate from staph because they are in a _____ versus cluster
streptococci
line
strep do not have ______ enzyme
catalase
strep can _______ RBCs
hemolyze
alpha hemolytic _____lyse, gamma “hemolytic” are unable to hemolyze. Beta completely lyse.
partially
________ are gram positive cocci in clusters
staphylococci
staphylococci have ________, blowing oxygen bubbles
catalase
staph are ____ hemolytic, so they fully lyse RBCs. They are _______ positive.
beta
coagulase
most staph are ______ resistant because they secrete penicillinase
penicillin
staphy aureus are also ______ resistant
methicillin (MRSA)
bacillus are gram ______, aerobic and ___ forming rods
positive
spore-forming
bacillus anthraces has a ______ that prevents phagocytosis. Spore activates in ____
capsule
bacillus cereus causes ______ _____
food poisoning
clostridium are ______ _____, spore forming rods
gram positive
clostridium is _____, and common in hospitals. Exotoxins are fatal.
anaerobic. examples: gas gangrene, tetanus, botulism
the most common cause of antibiotic diarrhea is ______ _____ (5-10 days post antibiotic)
clostridium difficile
C tetani is gram ______ rod, forms _______. Has a neurotoxic ______
positive
spores
exotoxin
clostridium botulinum is a gram ____ rod. Spores resist ______, and produces neurotoxin
positive
boiling
corynebacterium diphtheriae colonizes in the ______, forming a gray membrane
pharynx
corynebacterium diphtheriae is a gram _______ _____, but doesn’t for spores
positive rod
the gram positive rod with an endotoxin is _______
listeria
listeria is worrisome for neonates, ______ and immunocompromised. Hides in macrophages or neutrophils.
pregnancy