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RDS Test 2 > B8-082 Benign Uterine Disorders > Flashcards

B8-082 Benign Uterine Disorders Flashcards

1
Q

differential of AUB in postmenopausal females [3]

A

endometrial cancer
atrophic vaginitis
vaginal/cervical tumor

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2
Q

structural causes of AUB in females of reproductive age

A

Polyp
Adenomyosis
Leiomyoma
Malignancy

PALM

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3
Q

non-structural causes of AUB in females of reproductive age [5]

A

Coagulopathy (VWD)
Ovulatory disorder
Endometrial
Iatrogenic
Not otherwise classified

COEIN

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4
Q

benign collection of endometrial tissue in the uterine wall that extend into the uterine cavity

A

endometrial polyps

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5
Q

endometrial polyps grow in response to […]

A

estrogen

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6
Q

tamoxifen is a risk factor for the development of

A

endometrial polyps

(polyps should be removed to prevent malignancy)

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7
Q

evaluation of endometrial polyps should include [3]

A

TVUS
hysteroscopy
biopsy to confirm benign

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8
Q

treatment of endometrial polyps [3]

A

surgical removal
progestins
temporary GnRH analogs

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9
Q

endometrial polyp removal is always recommended for what patient population?

A

postmenopausal females

(highest risk of malignancy)

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10
Q

in premenopausal females, endometrial polyps greater than […] cm should be removed due to increased risk of malignancy

A

1.5

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11
Q

first-line imaging study for evaluation of AUB

A

TVUS

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12
Q

firm, mobile uterus that is nontender and enlarged with discrete nodules

A

leiomyoma

(may present with pelvic pain due to pressure of size of fibroid)

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13
Q

benign uterine tumor presenting with multiple, discrete tumors

A

uterine leiomyoma

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14
Q

prevalence of leiomyoma is higher in what patient populations?

A

african americans

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15
Q

sensitive to estrogen/progesterone levels
increased symptoms during pregnancy

A

leiomyoma

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16
Q

in a patient presenting with symptoms of leiomyoma, make sure to get what lab?

A

bHCG

17
Q

treatment for asymptomatic leiomyoma

A

observation

(will shrink postpartum/menopause)

18
Q

most frequently mutated gene in muliple leiomyomas

A

MED12

(mediator of RNA pol. II transcription)

19
Q

gene associated with large, singular leiomyomas

A

HMGA2

20
Q

enlarged, tender, boggy uterus

A

adenomyosis

21
Q

“venetian blinds” appearance on TVUS

A

adenomyosis

22
Q

[adenomyosis vs leiomyoma]

indistinct borders

A

adenomyosis

23
Q

[adenomyosis vs leiomyoma]

distinct, round borders

A

leiomyoma

24
Q

[adenomyosis vs leiomyoma]

thin, parallel, vertical shadowing on TVUS
“venetian blinds”

A

adenomyosis

25
Q

[adenomyosis vs leiomyoma]

dense with edge shadowing on TVUS

A

leiomyoma

26
Q

[adenomyosis vs leiomyoma]

tiny cysts/cystic striations

A

adenomyosis

27
Q

[adenomyosis vs leiomyoma]

solid cyst

A

leiomyoma

28
Q

[adenomyosis vs leiomyoma]

increased vascularity with penetrating vessels

A

adenomyosis

29
Q

[adenomyosis vs leiomyoma]

can be submucosal, intramural, or subserosal

A

leiomyoma

30
Q

[adenomyosis vs leiomyoma]

contiguous or centrally located in myometrium

A

adenomyosis

31
Q

diffusely enlarged uterus with some cystic areas within myometrium

A

adenomyosis

32
Q

initial test to order in patient with enlarged uterus

A

bHCG

33
Q

most effective treatment for patients with adenomyosis

A

levonorgestrel releasing IUD

mirena

34
Q

treatment of adenomyosis when fertility is not a consideration

A

hysterectomy

(cannot “cut out” adenomyosis like you can fibroids)

35
Q

risk factors for adenomyosis

A

multiparous
c-section
endometrial curettage/evacuation

(inside out theory mediated via TIAR pathway)

36
Q

treatment for symptom resolution of leiomyoma

A

oral contraceptives

37
Q

myomectomy is a viable treatment option for [adenomyosis/leiomyoma]

A

leiomyoma

38
Q

develops outside the uterus, and is therefore not associated with uterine bleeding

A

endometriosis

RDS Test 2 (21 decks)

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