B8-012 Contraception Flashcards
progestin inhibits ovulation by […] suppression
LH
[…] thickens the cervical mucus, preventing sperm transport
progestin
what type of contraception is contraindicated in patients who experience migraine with aura?
combined hormonal contraception (CHC)
(vision changes, numbness, parasthesias)
what schedule of combined oral contraceptive pills have been shown to have improved efficacy?
shortened hormone free week
(24 days on 4 days off)
what would an ideal OCP look like?
30 mcg EE + levonorgestrel
shortened/erased placebo week
monophasic
CHC patches may have lower efficacy in what patient populations?
obese patients
NuvaRing lasts […] month(s)
one
*new ring every month
Annovera (contraceptive ring) lasts […] month(s)
12
*same ring for 12 months, in for 24 days out for 4
what forms of CHC can be used continuously?
ring and pill
what forms of CHC cannot be used continuously?
patch
breast cancer in CHC users usually occurs in women in what age range?
40s
(RR of breast cancer due to CHC use is very low)
patients who use estrogen containing contraception have lower rates of what cancers? [3]
ovarian
colon
endometrial
there is a known causal link between estrogen and what chronic disease?
hypertension
CHCs raise systolic BP by […] mmhg and diastolic by […]mmhg
CHCs raise systolic BP by [8] mmhg and diastolic by [6]mmhg
what type of contraception is contraindicated in patients with hypertension?
CHC
(increased risk of MI, ischemic stroke)
do progestin only contraceptives still carry risk of VTE?
no
(suitable option for women with hx/risk factors of VTE)
progestin only pills (POPs) [2]
norethindrone (micronor)
drospirenon (slynd)
[norethindrone vs drospirenon]
primary mechanism: cervical mucus thickening
norethindrone (POP)
[norethindrone vs drospirenon]
primary mechanism: inhibits ovulation
drospirenon (POP)
[norethindrone vs drospirenon]
requires extremely punctual dosing
if the dosing is more than 3 hrs late, need to use a backup for 48 hrs
norethindrone (POP)
[norethindrone vs drospirenon]
window for missed pill is 24 hours
drospirenon (POP)
how can you be “reasonably sure” a patient is not pregnant?
actively menstruating
hasn’t had sex since last period
reliably using a form of birth control
within 7 days of spontaneous or induced abortion
4 weeks postpartum
fully or nearly fully breastfeeding
what are the risks of giving progesterone/estrogen in pregnancy?
none
(so can start any form of hormonal contraception and do a pregnancy test in 2-4 weeks if unsure a patient is pregnant; cannot use IUD though)
why are women with obesity are at a higher risk of endometrial cancer? [2]
increased peripheral conversion of estrogen
higher rates of anovulation
(contraception offsets risk)
IUDs decrease the risk of […] cancer
endometrial
what type of IUD actually reverses 90% of benign endometrial hyperplasia?
LNG-IUD