B7-036 Head and Neck Embryology Flashcards

1
Q

the mesenchymal core of the pharyngeal arches is derived from [2]

A

mesoderm
neural crest

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2
Q

congenital defects caused by a failure of neural crest cells to migrate to the first pharyngeal arch

A

neurochristopathy

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3
Q

DiGeorge syndrome is an example of a […] deriving from the 1st pharyngeal pouch

A

neurochristopathy

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4
Q

CATCH 22 for DiGeorge

A

Cardiac abnormalities
Abnormal facies
Thymic aplasia
Cleft palate
Hypocalcemia/hypoparathyroidism
deletion of chromosome 22

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5
Q

what gene is associated with DiGeorge syndrome?

A

TBX 1

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6
Q

the third aortic arch that passes through the 3rd pharyngeal pouch persists as the […]

A

internal carotid

(and part of the common carotid)

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7
Q

the fourth aortic arch that passes through the 4th pharyngeal pouch persists as the […]

A

right: subclavian
left: arch of aorta

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8
Q

1st pharyngeal pouch is innervated by

A

CN V

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9
Q

2nd pharyngeal pouch is innervated by

A

CN VII

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10
Q

3rd pharyngeal pouch is innervated by

A

CN IX

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11
Q

4th pharyngeal pouch is innervated by

A

CN X

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12
Q

1st arch muscles [2]

A

muscles of mastication
anterior belly of digastric

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13
Q

2nd arch muscles [2]

A

facial muscles of expression
posterior belly of digastric

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14
Q

3rd arch muscles

A

stylopharyngeous muscle

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15
Q

4t-6th arch muscles [2]

A

muscles of pharnyx
muscles of larynx

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16
Q

1st arch cartilage derivatives [3]

A

Meckel’s cartilage
malleus
incus

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17
Q

2nd arch cartilage derivatives [3]

A

stapes
styloid process
part of hyoid

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18
Q

3rd arch cartilage derivatives

A

part of hyoid and greater horn

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19
Q

4th-6th arch cartilage derivatives [2]

A

thyroid cartilage
cricoid cartilage

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20
Q

the pulmonary artery arises from

A

5th- 6th arch

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21
Q

the superior parathyroid gland originates from the […] pouch

A

4th

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22
Q

the inferior parathyroid gland originates from the […] pouch

A

3rd

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23
Q

the thyroid gland originates from the […] pouch

A

3rd

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24
Q

the external auditory meatus is derived from

A

1st pharyngeal cleft

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25
the cervical sinus is derived from
pharyngeal clefts 2,3,4
26
the tympanic cavity and auditory tube are derived from
1st pharyngeal pouch
27
the palatine tonsils are derived from
2nd pharyngeal pouch
28
fistulas/cysts derived from pharyngeal misdevelopment of the cervical sinus will be [...] in the neck
lateral
29
thyroglossal cysts appear in the [...] of the neck
midline
30
what pharyngeal arch does the anterior 2/3 of the tongue derive from?
1st
31
what pharyngeal arch does the posterior 1/3 of the tongue derive from?
3rd
32
what pharyngeal arch does the base of the tongue derive from?
4th
33
what nerve does general sensory to the anterior 2/3 of the tongue?
CN V3 via lingual
34
what nerve does general sensory to the posterior 1/3 of the tongue?
CN IX
35
what nerve does general sensory to the base of the tongue?
CN X
36
what nerve does general sensory to the epiglottis?
CN X
37
what nerve does taste to the anterior 2/3 of the tongue?
CN VII via chorda tympani
38
what nerve does taste to the posterior 1/3 of the tongue?
CN IX
39
what nerve does taste to the base of the tongue/epiglottis?
CN X
40
[...] somites form the musculature of the tongue
occipital
41
innervates the intrinsic muscles of the tongue
CN XII
42
provides motor to the palatoglossus
CN X
43
cleft lip (with or without palate) is more common in [males/females]
males
44
isolated cleft palate is more common in [males/females]
females
45
most common CL/P syndrome
van der woode syndrome
46
van der woode syndrome is caused by a mutation in
IRF6
47
lip pits cleft lip and/or palate missing teeth
van der woode syndrome
48
label the structures
49
the maxillary process fuses to the [...] process
medial nasal
50
what facial prominence forms the forehead and bridge of nose?
frontonasal
51
what facial prominence forms the cheeks and some of upper lip?
maxillary
52
what facial prominence forms the philtrum of upper lip, crest, and tip of nose?
medial nasal
53
what facial prominence forms the alae of the nose?
lateral nasal
54
what facial prominence forms the lower lip?
mandibular
55
loss of fusion of the maxillary process and medial nasal process results in
cleft lip
56
secondary palate is an extension of
maxillary process
57
micrognathia causes glossoptosis which prevents the elevation of the secondary palate, resulting in cleft palate
pierre-robin sequence
58
period of gestation with greatest sensitivity to alcohol
first month
59
known to cause apoptosis of neural crest cells
alcohol
60
which aortic arch persists as a stem of the internal carotid?
3rd (supplies blood to most of the head and neck)
61
4th aortic arch persists as [...] on the right
proximal subclavian a.
62
4th aortic arch persists as [...] on the left
part of the arch of the aorta
63
6th aortic arch persists as [2]
pulmonary arteries ductus arteriosus
64
a thyroglossal duct would be found [...]
midline
65
a pharyngeal fistula would be found [...]
lateral
66
a persistent [...] pouch would be associated with ear abnormalitis
1st
67
bones of the middle ear are derived from
neural crest
68
intrinsic tongue muscles are derived from
occipital myotomes
69
parathyroid glands are derived from
3rd (inferior) and 4th (superior) pharyngeal pouches
70
the thymus is derived from
3rd pharyngeal pouch
71
the muscles of facial expression are derived from
2nd pharyngeal pouch
72
the external ear derives from
1st pharyngeal cleft
73
maxilla and mandible are derived from
1st pharyngeal pouch
74
the stylopharyngeus muscle is derived from
3rd pharyngeal arch
75
a non-midline cleft lip results from
failure of maxillary processes to fuse with the medial nasal process
76
a midline cleft lip results from
failure of globular processes to fuse
77
a cleft palate results from
failure of the palatal processes to fuse
78
midline cyst with abnormal thyroid scan indicates
thyroid ectopia
79
downward-slanting eyes, very small jaw and chin, hearing loss, and vision loss
Treacher Collins Syndrome
80
gene associated with Treacher Collins
TCOF1 Autosomal dominant pattern