B7-036 Head and Neck Embryology Flashcards

1
Q

the mesenchymal core of the pharyngeal arches is derived from [2]

A

mesoderm
neural crest

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2
Q

congenital defects caused by a failure of neural crest cells to migrate to the first pharyngeal arch

A

neurochristopathy

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3
Q

DiGeorge syndrome is an example of a […] deriving from the 1st pharyngeal pouch

A

neurochristopathy

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4
Q

CATCH 22 for DiGeorge

A

Cardiac abnormalities
Abnormal facies
Thymic aplasia
Cleft palate
Hypocalcemia/hypoparathyroidism
deletion of chromosome 22

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5
Q

what gene is associated with DiGeorge syndrome?

A

TBX 1

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6
Q

the third aortic arch that passes through the 3rd pharyngeal pouch persists as the […]

A

internal carotid

(and part of the common carotid)

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7
Q

the fourth aortic arch that passes through the 4th pharyngeal pouch persists as the […]

A

right: subclavian
left: arch of aorta

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8
Q

1st pharyngeal pouch is innervated by

A

CN V

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9
Q

2nd pharyngeal pouch is innervated by

A

CN VII

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10
Q

3rd pharyngeal pouch is innervated by

A

CN IX

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11
Q

4th pharyngeal pouch is innervated by

A

CN X

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12
Q

1st arch muscles [2]

A

muscles of mastication
anterior belly of digastric

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13
Q

2nd arch muscles [2]

A

facial muscles of expression
posterior belly of digastric

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14
Q

3rd arch muscles

A

stylopharyngeous muscle

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15
Q

4t-6th arch muscles [2]

A

muscles of pharnyx
muscles of larynx

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16
Q

1st arch cartilage derivatives [3]

A

Meckel’s cartilage
malleus
incus

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17
Q

2nd arch cartilage derivatives [3]

A

stapes
styloid process
part of hyoid

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18
Q

3rd arch cartilage derivatives

A

part of hyoid and greater horn

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19
Q

4th-6th arch cartilage derivatives [2]

A

thyroid cartilage
cricoid cartilage

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20
Q

the pulmonary artery arises from

A

5th- 6th arch

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21
Q

the superior parathyroid gland originates from the […] pouch

A

4th

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22
Q

the inferior parathyroid gland originates from the […] pouch

A

3rd

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23
Q

the thyroid gland originates from the […] pouch

A

3rd

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24
Q

the external auditory meatus is derived from

A

1st pharyngeal cleft

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25
Q

the cervical sinus is derived from

A

pharyngeal clefts 2,3,4

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26
Q

the tympanic cavity and auditory tube are derived from

A

1st pharyngeal pouch

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27
Q

the palatine tonsils are derived from

A

2nd pharyngeal pouch

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28
Q

fistulas/cysts derived from pharyngeal misdevelopment of the cervical sinus will be […] in the neck

A

lateral

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29
Q

thyroglossal cysts appear in the […] of the neck

A

midline

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30
Q

what pharyngeal arch does the anterior 2/3 of the tongue derive from?

A

1st

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31
Q

what pharyngeal arch does the posterior 1/3 of the tongue derive from?

A

3rd

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32
Q

what pharyngeal arch does the base of the tongue derive from?

A

4th

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33
Q

what nerve does general sensory to the anterior 2/3 of the tongue?

A

CN V3 via lingual

34
Q

what nerve does general sensory to the posterior 1/3 of the tongue?

A

CN IX

35
Q

what nerve does general sensory to the base of the tongue?

A

CN X

36
Q

what nerve does general sensory to the epiglottis?

A

CN X

37
Q

what nerve does taste to the anterior 2/3 of the tongue?

A

CN VII via chorda tympani

38
Q

what nerve does taste to the posterior 1/3 of the tongue?

A

CN IX

39
Q

what nerve does taste to the base of the tongue/epiglottis?

A

CN X

40
Q

[…] somites form the musculature of the tongue

A

occipital

41
Q

innervates the intrinsic muscles of the tongue

A

CN XII

42
Q

provides motor to the palatoglossus

A

CN X

43
Q

cleft lip (with or without palate) is more common in [males/females]

A

males

44
Q

isolated cleft palate is more common in [males/females]

A

females

45
Q

most common CL/P syndrome

A

van der woode syndrome

46
Q

van der woode syndrome is caused by a mutation in

A

IRF6

47
Q

lip pits
cleft lip and/or palate
missing teeth

A

van der woode syndrome

48
Q

label the structures

A
49
Q

the maxillary process fuses to the […] process

A

medial nasal

50
Q

what facial prominence forms the forehead and bridge of nose?

A

frontonasal

51
Q

what facial prominence forms the cheeks and some of upper lip?

A

maxillary

52
Q

what facial prominence forms the philtrum of upper lip, crest, and tip of nose?

A

medial nasal

53
Q

what facial prominence forms the alae of the nose?

A

lateral nasal

54
Q

what facial prominence forms the lower lip?

A

mandibular

55
Q

loss of fusion of the maxillary process and medial nasal process results in

A

cleft lip

56
Q

secondary palate is an extension of

A

maxillary process

57
Q

micrognathia causes glossoptosis which prevents the elevation of the secondary palate, resulting in cleft palate

A

pierre-robin sequence

58
Q

period of gestation with greatest sensitivity to alcohol

A

first month

59
Q

known to cause apoptosis of neural crest cells

A

alcohol

60
Q

which aortic arch persists as a stem of the internal carotid?

A

3rd

(supplies blood to most of the head and neck)

61
Q

4th aortic arch persists as […] on the right

A

proximal subclavian a.

62
Q

4th aortic arch persists as […] on the left

A

part of the arch of the aorta

63
Q

6th aortic arch persists as [2]

A

pulmonary arteries
ductus arteriosus

64
Q

a thyroglossal duct would be found […]

A

midline

65
Q

a pharyngeal fistula would be found […]

A

lateral

66
Q

a persistent […] pouch would be associated with ear abnormalitis

A

1st

67
Q

bones of the middle ear are derived from

A

neural crest

68
Q

intrinsic tongue muscles are derived from

A

occipital myotomes

69
Q

parathyroid glands are derived from

A

3rd (inferior) and 4th (superior) pharyngeal pouches

70
Q

the thymus is derived from

A

3rd pharyngeal pouch

71
Q

the muscles of facial expression are derived from

A

2nd pharyngeal pouch

72
Q

the external ear derives from

A

1st pharyngeal cleft

73
Q

maxilla and mandible are derived from

A

1st pharyngeal pouch

74
Q

the stylopharyngeus muscle is derived from

A

3rd pharyngeal arch

75
Q

a non-midline cleft lip results from

A

failure of maxillary processes to fuse with the medial nasal process

76
Q

a midline cleft lip results from

A

failure of globular processes to fuse

77
Q

a cleft palate results from

A

failure of the palatal processes to fuse

78
Q

midline cyst with abnormal thyroid scan indicates

A

thyroid ectopia

79
Q

downward-slanting eyes, very small jaw and chin, hearing loss, and vision loss

A

Treacher Collins Syndrome

80
Q

gene associated with Treacher Collins

A

TCOF1

Autosomal dominant pattern