B4W1 Trans Flashcards

1
Q

Diagnoses of Diabetes

A

Fasting Blood Glucose of >126 mg/dl
Random Glucose of >200 mg/dl

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2
Q

Type 1 Diabetes

A

loss of insulin production

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3
Q

Type 2 Diabetes

A

Initial insulin resistance
B-Cell failure and decreased insulin secretion

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4
Q

Thrifty Gene Hypothesis

A

Proposal that genes that lead to diabetes were helpful in situations in which food was scarce

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5
Q

Risk Factors for Diabetic Kidney Disease

A

Race/Genetics, Gender, Obesity, Poor Glycemic Control, Hypertension and diabetic complications

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6
Q

Trend of Type 1 Diabetes GFR and Albumin Excretion

A

Around 16 years after onset Albumin excretion increases and GFR decreases

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7
Q

Diagnoses of Diabetic Kidney Disease

A

Low GFR <60 ml/min
Albuminuria or Albumin in Urine >30 mg albumin or 300 mg protein per 24 hours of urine collected

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8
Q

Streptozotocin Medication

A

Medication initially proposed as an antibiotic but was found to be toxic to B-Cells and cause diabetes in animals

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9
Q

Role of Leptin

A

Leptin is found within adipose tissue and inhibits insulin release and suppresses appetite

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10
Q

Intraglomerular Hypertension and Hyperfiltration

A

Hypertension leads to an increase in blood flow within the glomerulus

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11
Q

Endothelin Effect on Na reabsorbtion

A
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