B4-071 Vasculitides Flashcards

1
Q

most commonly affects branches of carotid artery

A

giant cell arterits

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2
Q

most common form of vasculitis among elderly and adults in US and europe

A

giant cell arteritis

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3
Q

headaches
jaw claudication
ischemic optic neuropathy

A

giant cell arteritis

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4
Q
  • infiltrate of T cells and macrophages
  • multinucleated giant cells
A

giant cell arteritis

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5
Q

ocular symptoms

A

giant cell arteritis

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6
Q

pulseless disease

A

takayasu arteritis

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7
Q

marked weakening of pulses in upper extremities

A

takayasu arteritis

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8
Q

thickening and narrowing of aortic arch and proximal great vessels

A

takayasu arteritis

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9
Q
  • large vessel vasculitis
  • patient is under 50
A

takayasu arteritis

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10
Q
  • large vessel vasculitis
  • patient is over 50
A

giant cell arteritis

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11
Q

1/3 of patient have hepatitis B

A

polyarteritis nodosa

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12
Q
  • involves renal and visceral vessels
  • spares pulmonary circulation
A

polyarteritis nodosa

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13
Q

string of pearls

A

polyarteritis nodosa

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14
Q

different stages of activity coexist in the same vessel

A

polyarteritis nodosa

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15
Q
  • rapidly accelerating hypertension
  • abdominal pain
  • bloody stools
A

polyarteritis nodosa

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16
Q

self limited illness of infancy and childhood

A

kawasaki disease

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17
Q

children under 4

A

kawasaki disease

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18
Q
  • conjunctival and oral erythema and blistering
  • edema of hands and feet
  • erythema of palms and soles
A

kawasaki disease

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19
Q

treat with IV Ig and aspirin

A

kawasaki

20
Q
  • affects capillaries, arterioles and venules
  • all lesion tend to be of same age
A

microscopic polyangitis

21
Q

affects skin, mucous membranes, lungs, brain, heart, GI, kidney, muscle

A

microscopic polyangitis

22
Q
  • necrotizing glomerulonephritis
  • pulmonary capillaritis
A

microscopic polyangitis

23
Q

MPO ANCAs

2

A

microscopic polyangitis
Churg-Strauss

24
Q
  • hemoptysis
  • hematuria/proteinuria
  • bowel pain
  • palpable purpura
A

microscopic polyangitis

25
Q

extravasation of RBCs
pauci-immune injury

A

microscopic polyangitis

26
Q

acute necrotizing granulomas of respiratory tract

A

GPA

27
Q

focal necrotizing, often crescentic glomerulonephritis

A

GPA

28
Q

PR3 ANCAs

A

GPA

29
Q
  • focal necrotizing vasculitis
  • necrotizing granulomas in lung and upper airway
  • necrotizing glomerulonephritis
A

GPA

30
Q

bilateral pneumonitis with nodules and cavitary lesions

A

GPA

31
Q

chronic sinusitis

A

GPA

32
Q

mucosal ulcerations of nasopharynx

A

GPA

33
Q

similar to GPA without nasopharyngeal involvement

A

microscopic polyangitis

34
Q
  • asthma
  • allergic rhinitis
  • peripheral eosinophilia
A

churg-strauss

35
Q

palpable purpura
GI bleeding

A

churg-strauss

36
Q

both granulomas and eosinophils

A

churg-strauss

37
Q

occurs in heavy smokers

A

thromboangitis obliterans
Buerger disease

38
Q

may cause gangrene/amputaion of digits

A

Buerger disease

39
Q

raynaud phenomenon

A

Buerger disease

40
Q
  • small microabscesses
  • extends into contiguous veins and nerves
A

Buergers

41
Q

linear deposits of IgG and C3 in GBM

A

goodpastures

42
Q

pulmonary hemorrhage associated with renal failure

A

goodpastures

43
Q

treatment for goodpastures

A

plasmapheresis

44
Q
  • purpuric skin lesions-extensor surfaces of arms, legs, buttocks
  • abdominal pain
  • intestinal bleeding
  • arthralgias
A

Henoch-schonlein

45
Q

IgA deposits

A

Henoch-Schonlein

46
Q
  • IgG-IgM complexes
  • cutaneous vasculitis
  • synovitis
A

mixed cryoglobulinemia

47
Q

associated with hepatitis C

A

mixed cryoglobulinemia