B4-071 Vasculitides Flashcards
most commonly affects branches of carotid artery
giant cell arterits
most common form of vasculitis among elderly and adults in US and europe
giant cell arteritis
headaches
jaw claudication
ischemic optic neuropathy
giant cell arteritis
- infiltrate of T cells and macrophages
- multinucleated giant cells
giant cell arteritis
ocular symptoms
giant cell arteritis
pulseless disease
takayasu arteritis
marked weakening of pulses in upper extremities
takayasu arteritis
thickening and narrowing of aortic arch and proximal great vessels
takayasu arteritis
- large vessel vasculitis
- patient is under 50
takayasu arteritis
- large vessel vasculitis
- patient is over 50
giant cell arteritis
1/3 of patient have hepatitis B
polyarteritis nodosa
- involves renal and visceral vessels
- spares pulmonary circulation
polyarteritis nodosa
string of pearls
polyarteritis nodosa
different stages of activity coexist in the same vessel
polyarteritis nodosa
- rapidly accelerating hypertension
- abdominal pain
- bloody stools
polyarteritis nodosa
self limited illness of infancy and childhood
kawasaki disease
children under 4
kawasaki disease
- conjunctival and oral erythema and blistering
- edema of hands and feet
- erythema of palms and soles
kawasaki disease
treat with IV Ig and aspirin
kawasaki
- affects capillaries, arterioles and venules
- all lesion tend to be of same age
microscopic polyangitis
affects skin, mucous membranes, lungs, brain, heart, GI, kidney, muscle
microscopic polyangitis
- necrotizing glomerulonephritis
- pulmonary capillaritis
microscopic polyangitis
MPO ANCAs
2
microscopic polyangitis
Churg-Strauss
- hemoptysis
- hematuria/proteinuria
- bowel pain
- palpable purpura
microscopic polyangitis
