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CP Test 2 > B4-069 Cardiomyopathies > Flashcards

B4-069 Cardiomyopathies Flashcards

1
Q

most common cardiomyopathy

A

dilated

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2
Q

leads to systolic dysfunction

A

dilated

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3
Q

familial dilated cardiomyopathy is caused by a mutation in what protein?

A

titin

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4
Q

heart failure
S3 sound
sytolic regurgitant murmur

A

dilated cardiomyopathy

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5
Q

balloon appearance of heart on CXR

A

dilated cardiomyopathy

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6
Q

caused by mutations in myosin binding protein C and beta myosin heavy chains

A

hypertrophic cardiomyopathy

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7
Q

causes syncope during exercise, may lead to SCD

A

hypertrophic cardiomyopathy

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8
Q

S4 sound
systolic murmur
maybe mitral regurg

A

hypertrophic cardiomyopathy

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9
Q

cause diastolic dysfunction

2

A

hypertrophic cardiomyopathy
retrictive cardiomyopathy

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10
Q

eccentric hypertrophy

A

dilated cardiomyopathy

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11
Q

concentric hypertrophy
septal predominance

A

hypertrophic cardiomyopathy

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12
Q

most common genetic heart disease
most frequent cause of sudden cardiac death in young people

A

hypertrophic

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13
Q
  • globoid
  • markedly enlarged
A

dilated cardiomyopathy

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14
Q

strong alcohol use association

A

dilated cardiomyopathy

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15
Q

excess catecholamines
pheochromocytoma

A

dilated cardiomyopathy

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16
Q

subendocardial scars
mural thrombi

A

dilated cardiomyopathy

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17
Q

ejection fraction less than 25%

A

dilated cardiomyopathy

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18
Q

massive myocardial hypertrophy without ventricular dilation

A

hypertrophic cardiomyopathy

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19
Q

massive myocyte hypertrophy
haphazard disarray of bundles of myocytes

A

hypertrophic cardiomyopathy

20
Q

cavities are not dilated
myocardium largely unremarkable

A

restrictive cardiomyopathy

21
Q

name that restrictive cardiomyopathy

  • children and YA
  • linked to nutritional deficiencies and parasitic infections
  • most common form worldwide
A

endomyocardial fibrosis

22
Q

name that restrictive cardiomyopathy

  • large mural thrombi
  • peripheral eosinophilia
  • associated with PDGFR
A

loeffler endomyocarditis

23
Q
  • fibroelastic thickening involving LV
  • most common in first 2 years of life
  • genetic
A

endocardial fibroelastosis

24
Q

non-caseating, non-necrotizing granulomas

A

sarcoidosis

restrictive

25
Q
  • autosomal disorder
  • causes right sided HF and rhythm disturbances
  • massive fatty infiltration and focal fibrosis
A

arrhythmogenic cardiomyopathy

26
Q

most common viral causes of myocarditis in US

A
  • coxsackie
  • CMV
  • HIV
  • influenza
27
Q

non viral causes of myocarditis

A
  • T. cruzi
  • Trichinosis
  • Toxoplasmosis
  • Lyme
  • Diptheria
28
Q
  • interstitial inflammatory infiltrate
  • diffuse, mononuclear lymphocytic infiltrate
A

myocarditis

29
Q

hypersensitivity myocarditis is characterized by what pathologic finding?

A

eosinophils

30
Q

associated with pregnancy

A

dilated cardiomyopathy

31
Q

what inheritance pattern is associated with HCM

A

autosomal dominant

32
Q

stiff, non compliant myocardium

A

restrictive cardiomyopathy

33
Q

amyloidosis causes what kind of cardiomyopathy?

A

restrictive

34
Q

increased interstitial fibrosis due to radiation causes

A

restrictive cardiomyopathy

35
Q

cobalts
anthracyclines
cocaine
cyclophosphamide

are associated with

A

dilated cardiomyopathy

36
Q

ejection fraction between 50-80%

A

hypertrophic cardiomyopathy

37
Q
  • fatal condition
  • multiple non-caseating granulomas
  • multinucleated giant cells
  • ventricular arrhythmia or heart block
A

giant cell myocarditis

38
Q

most common identifiable cause of dilated cardiomyopathy in US and Europe

A

alcholic use disorder cardiomyopathy

39
Q

correlated to total lifetime dose of ethanol

A

degree of myocardial damage

40
Q

can alcohol abstinence reverse cardiomyopathy?

A

only in early stages

41
Q

trypanosomes

A

myocarditis due to chagas

42
Q

can occur in late pregnancy or up to a few months postpartum

A

peripartum cardiomyopathy

43
Q

can present one month to one year or more after termination of therapy

A

doxorubicin induced heart failure

44
Q

chemotherapy agent that can cause cardiomyopathy

A

doxorubicin

45
Q

LVH without indentifiable cause

A

HCM

CP Test 2 (16 decks)

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