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CP Test 2 > B4-020 Cell Biology and Histology of the Vascular System > Flashcards

B4-020 Cell Biology and Histology of the Vascular System Flashcards

(60 cards)

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1
Q

walls of ateries

A
  1. tunica intima (innermost)
  2. tunica media
  3. tunica externa (outermost)
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2
Q

lining of endothelial cells, subendothelian basement membrane and loose connective tissue, internal elastic lamina

A

tunica intima

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3
Q

concentric layers of smooth muscle, collagen fibers, external elastic lamina

A

tunica media

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4
Q

connective tissue

A

tunica externa

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5
Q

have many elastic lamella in the tunica media

A

large arteries

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6
Q

prominent internal elastic lamina

A

muscular arteries

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7
Q
  • major determinants of systolic blood pressure
  • regulate vascular tone
A

arterioles

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8
Q

2-5 concentric layers of vascular smooth muscle in tunica media

A

arterioles

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9
Q
A

large artery

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10
Q
A

medium/muscular artery

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11
Q
A

arteriole

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12
Q

thin tubes consisting of only basement membrane

A

capillary

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13
Q

permit the passage of 1 RBC at a time

A

capillary

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14
Q

3 types of capillaries

A
  • continuous
  • fenestrated
  • discontinous
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15
Q

continous capillaries can be found in what tissues

A

muscle, brain, thymus, lung

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16
Q

fenestrated capillaries can be found in what tissue

A

intestines, kidneys

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17
Q

discontinuous capillaries can be found in what tissues

A

liver, speen, bone marrow

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18
Q

what type of capillary requires vesicles?

A

continuous

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19
Q
A

continous capillary

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20
Q
A

fenestrated capillary

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21
Q

caveolae

A

transport vesicle

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22
Q
  • contractile cells surround capillaries
  • thought to regulate blood flow
  • role in angiogenesis
A

pericytes

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23
Q

loss of pericyte function in the CNS causes

A

increased permeability of blood-brain barrier

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24
Q

preferred site of diapedesis

A

veins

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25
find: lymphatic vessel, venules, & arterioles
26
veins have [...] to prevent the reflux of blood
valves
27
* distinction between t. media and t. externa often unclear * t. media thinner
veins
28
how to risk factors lead to the progression of atherosclerosis and CVD?
cause oxidative stress --> endothelial dysfunction --> reduced NO bioavailability
29
lack tight junctions
lymphatic epithelial cells
30
lymphatic vessel
31
lymphatic vessel with valve
32
creation of new vascular network
vasculogenesis
33
sprouting from exisiting network
angiogenesis
34
vasculogenesis and angiogenesis require
VEGF
35
key mediator of vessel growth
hypoxia
36
EPO and VEGF lead to
increased oxygen delivery
37
EPO/IGF2 and GLUT allow for
oxygen deprivation survival
38
targets VEGF, EPO, GLUT
HIF
39
40
required for both vasculogenesis and angiogenesis
VEGF
41
creates new vessels from endothelial precursor cells
vasculogenesis
42
creates new vessel via sprouting
angiogensis
43
breakdown of the vessels basal lamina is necessary for
angiogenesis
44
hemodynamic shear forces are minimized in
post capillary venules
45
resemble continous capillaries with a wider lumen do not have fenestrae
postcapillary venules
46
preferred site for leukocyte diapedesis
postcapillary venule
47
elastic lamella in tunica media
conducting arteries
48
internal elastic membrane is prominent
muscular arteries
49
elastic walls distend during systole and recoil during diastole so continous flow results
conducting arteries
50
longitudinal smooth muscle bundles in the adventitia and transverse smooth muscle in media
large vein
51
smooth muscle bundles run perpendicular to each other
large vein
52
lymphatic vessels drain into ducts that drain into
large veins
53
blood pressure is predominately regulated by
arterioles
54
blood leaves the heart via
elastic arteries
55
gas and nutrient exchange
capillaries
56
no gaps in endothelium
continous capillaries
57
lymph vessel drain into
lymphatic ducts
58
supplies blood to walls of large vessels
vaso vasorum
59
small endocytic vesicles and caveolae
continous capillaries
60
discontinous basal lamina and large gaps in endothelium
sinusoidal capillaries

CP Test 2 (16 decks)

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