Autonomic Pharmacology CIS Flashcards
alpha 1
stimulate contraction of smooth muscle
beta 2
relax smooth muscle
muscarinic
contract smooth muscle
ACh and muscarinic agonists
give IV
- vasodilation
- because of NO release
urination and defacation
parasympathetic
decreased motility and secretion of stomach
sympathetic
smooth muscle contraction
PS
smooth muscle relaxation
S
AChE inhibitor acute intoxication
SLUDGE
-salivation, lacrimation, urination, defecation, GI distress, emesis
antidiarrheal med
mAChR antagonist
diphenoxylate and atropine
atropine
lomotil
-antidiarrheal
pheochromocytoma
HA, perspiration, palpitation, anxiety
adrenal gland tumor
beta blocker in pheochromocytoma?
upopposed alpha stimulation (vasoconstriction)
will increased hypertension
blood vessel control?
alpha 1 - constriction
beta 2 - dilation
beta blocker?
will caused decreased heart rate and contractility
-however, blocks the dilation of blood vessels
vasoconstriction
clonidine suppression test
activates central alpha-2 receptor
-suppress catecholamine release
no effect on catecholamines from pheochromocytoma
organophosphates
AChE inhibitor
-can cause toxicity
SLUDGE
DUMBELS
decrease renin section
alpha 1
increase renin secretion
beta 1
oral beta antagonist for glaucoma?
contraindicated for asthma
-will cause bronchoconstriction
bladder control?
mAChR - facilitate urination
alpha 1 / beta 2 - inhibit urination
muscarinic antagonist
dry mouth / eyes, dizzy, blurry vision
salivation and lacrimation stimulation
parasympathetic
urination and defecation
parasympathetic
GI motility and secretion
parasympathetic
decreased GI motility and secretion
sympathetic
decreased urination
sympathetic
pupil constriction
myosis
parasympathetic
pupil dilation
mydriasis
sympathetic
