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Physio (self) > Autonomic Effects on Various Organs of the Body > Flashcards

Autonomic Effects on Various Organs of the Body Flashcards

(62 cards)

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1
Q

Stomach: Motility and Tone - Receptor Type

A

α2, β2

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2
Q

Stomach: Motility and Tone - Adrenergic Impulse/Response

A

Decrease (usually) +

It has been proposed that adrenergic fibers terminate at
* inhibitory β receptors on smooth muscle fibers
* inhibitory α receptors on parasympathetic cholinergic (excitatory) ganglion cells of the Auerbach plexus.

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3
Q

Stomach: Motility and Tone - Cholinergic Impulse/Response

A

Increase +++

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4
Q

Stomach: Pyloric Spinchters - Receptor Type

A

α1

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5
Q

Stomach: Pyloric Spinchters - α1 Adrenergic Impulse/Response

A

Contraction (usually) +

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6
Q

Stomach: Spinchters - α1 Cholinergic Impulse/Response

A

Relaxation (usually) +

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7
Q

Stomach: Secretion - Adrenergic Impulse/Response

A

Inhibition (?)

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8
Q

Stomach: Secretion - Cholinergic Impulse/Response

A

Stimulation +++

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9
Q

Intestine: Motility and Tone - Receptor Type

A

α2, β2

It has been proposed that adrenergic fibers terminate at
* inhibitory β receptors on smooth muscle fibers
* inhibitory α receptors on parasympathetic cholinergic (excitatory) ganglion cells of the Auerbach plexus.

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10
Q

Intestine: Motility and Tone - Adrenergic Impulse/Response

A

Decrease (usually) +

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11
Q

Intestine: Motility and Tone - Cholinergic Impulse/Response

A

Increase +++

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12
Q

Intestine: Spinchters - Receptor Type

A

α

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13
Q

Intestine: Spinchters - α Adrenergic Impulse/Response

A

Contraction (usually) +

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14
Q

Intestine: Spinchters - α Cholinergic Impulse/Response

A

Relaxation (usually) +

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15
Q

Intestine: Secretion - Adrenergic Impulse/Response

A

Inhibition (?)

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16
Q

Intestine: Secretion - Cholinergic Impulse/Response

A

Stimulation +++

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17
Q

Gallbladder and Bile Ducts - Adrenergic Impulse/Response

A

Relaxation +

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18
Q

Gallbladder and Bile Ducts - Cholinergic Impulse/Response

A

Contraction +

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19
Q

Liver: Receptor Type

A

α, β2

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20
Q

Liver: Adrenergic Impulse/Response β2

A

Glycogenolysis (Catabolic), gluconeogenesis (Anabolic) +++ : Glucose Released

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21
Q

Liver: Cholinergic Impulse/Response

A

Glycogen synthesis (Anabolic) +

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22
Q

Pancreas: Acini - Receptor Type

A

α2

Acini : Important for release of digestive juices

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23
Q

Pancreas: Acini - α2 Adrenergic Impulse/Response

A

Decreased secretion +

Acini : Important for release of digestive juices

SNS wants the catabolic pathways stimulated by the glucagon for energy source

Stimulate release of **glucagon from α cells **
Inhibit release of insulin from β cells

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24
Q

Pancreas: Acini - α2 Cholinergic Impulse/Response

A

Secretion +

Acini : Important for release of digestive juices

SNS wants the catabolic pathways stimulated by the glucagon for energy source

Stimulate release of **glucagon from α cells **
Inhibit release of insulin from β cells

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25
Pancreas: Islets (beta cells) - Receptor Type
α, β2 ## Footnote SNS wants the catabolic pathways stimulated by the glucagon for energy source Stimulate release of **glucagon from α cells ** Inhibit release of **insulin from β cells**
26
Pancreas: Islets (beta cells) - α Adrenergic Impulse/Response
Decreased secretion ++ ## Footnote SNS wants the catabolic pathways stimulated by the glucagon for energy source Stimulate release of **glucagon from α cells ** Inhibit release of **insulin from β cells**
27
Pancreas: Islets (beta cells) - β2 Adrenergic Impulse/Response
Increased secretion + ## Footnote SNS wants the catabolic pathways stimulated by the glucagon for energy source Stimulate release of **glucagon from α cells ** Inhibit release of **insulin from β cells**
28
Pancreas: Fat cells - Receptor Type
α, β1 ## Footnote SNS wants the catabolic pathways stimulated by the glucagon for energy source Stimulate release of **glucagon from α cells ** Inhibit release of **insulin from β cells**
29
Pancreas: Fat cells - Adrenergic Impulse/Response
Lipolysis +++ ## Footnote SNS wants the catabolic pathways stimulated by the glucagon for energy source Stimulate release of **glucagon from α cells ** Inhibit release of **insulin from β cells**
30
Pancreas: Salivary glands - α Adrenergic Impulse/Response
K+ and water secretion +
31
Pancreas: Salivary glands - α Cholinergic Impulse/Response
K+ and water secretion +++
32
Pancreas: Salivary glands - β Adrenergic Impulse/Response
Amylase secretion +
33
Pancreas: Lacrimal glands - Cholinergic Impulse/Response
Secretion ++
34
Pancreas: Nasopharyngeal glands - Cholinergic Impulse/Response
Secretion ++
35
Pancreas: Pineal gland - β Adrenergic Impulse/Response
Melatonin synthesis
36
Arterioles: Salivary Gland - Receptor Type
α
37
Arterioles: Salivary Gland - α1 Adrenergic Impulse/Response
Constriction +++ ## Footnote Blood vessels: constriction → ↓water and gland electrolytes to be mixed with the saliva
38
Arterioles: Salivary Gland - α Adrenergic Impulse/Response
Dilation ++
39
Glands: Effect of Sympathetic Stimulation : β2 ## Footnote Nasal Lacrimal Parotid Submandibular Gastric Pancreatic
Vasoconstriction and slight secretion | SNS (B2): NE/VasoCONSTRICTION ## Footnote Producton of THICKER SALIVA Contains β2 adrenergic receptors o Switches salivary secretions into making *Decrease water and electrolyte-rich saliva *Increase mucin proteins *Increase different salivary enzymes *End result: thicker saliva Blood vessels going to the salivary glands contain α1 adrenergic receptors → constricts blood vessels → ↓blood flow → ↓water and electrolytes to be mixed with the saliva
40
Glands: Effect of Parasympathetic Stimulation : M3 ## Footnote Nasal Lacrimal Parotid Submandibular Gastric Pancreatic
Stimulation of copious secretion (containing many enzymes for enzyme-secreting glands) | PNS (M3) : ACh/VasoDILATION
41
Gut: Lumen - Effect of Sympathetic Stimulation
Decreased peristalsis and tone
42
Gut: Lumen - Effect of Parasympathetic Stimulation
Increased peristalsis and tone
43
Gut: Sphincter - Effect of Sympathetic Stimulation
Increased tone (most times)
44
Gut: Sphincter - Effect of Parasympathetic Stimulation
Relaxed (most times)
45
Blood: Glucose - Effect of Sympathetic Stimulation
Increased
46
Blood: Glucose - Effect of Parasympathetic Stimulation
No Effect
47
Basal metabolism - Effect of Sympathetic Stimulation
Increased up to 100%
48
Basal metabolism - Effect of Parasympathetic Stimulation
No Effect
49
GI Tract - SNS β2 (Smooth Muscle)
Relaxation of Smooth Muscle
50
GI Tract - SNS α1 (Smooth Muscle)
Constriction
51
Adipose tissues: SNS Response β3
Stimulates lipolysis ## Footnote Breakdown lipids for energy source
52
Gastric Glands:Parietal Cells- PNS M1
Increase Secretion
53
Exocrine Glands: PNS M3 ## Footnote Lacrimal gland salivary glands, sweat glands, pancreatic acini, gastric glands
Increase Secretion
54
GI tract (smooth muscles): PNS M3
Increase peristalsis (Contraction) , segmentation, HCl secretion, pepsinogen and intestinal secretion. | PNS: M3 / Always wet/contracts/constricts
55
Internal anal sphincter: PNS M3
Increase contraction: Defacation
56
Blood Flow to the GIT : SNS α1
Vasoconstriction Increase Ca++
57
Stimulates PLC → ↑DAG, IP3 → activates PKC, ↑↑Ca2+ → phosphorylate different proteins and enzymes
α1/Gq
58
Inhibits adenylyl cyclase → ↓cAMP → inhibits PKA → inhibits phosphorylation ↑K+ channel permeability → ↑K+ efflux → cell hyperpolarization
α2/Gi
59
Activates adenylyl cyclase → ↑cAMP → stimulates PKA → stimulates phosphorylation
β1/2/3 :Gs
60
Sympathetic Receptor/s for Smooth Muscles
α1 and β2
61
Sympathetic Receptor/s for Kidney and Heart
β1
62
Sympathetic Receptor/s for Adipose and Bladder
β3

Physio (self) (17 decks)

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