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USMLE > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

Anti-ACh receptor

A

Myasthenia gravis

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2
Q

Anti-basement membrane

A

Goodpasture syndrome

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3
Q

Anti-cardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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4
Q

Anticentromere

A

Limited scleroderma (CREST syndrome)

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5
Q

Anti-desmoglein

A

Pemphigus vulgaris

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6
Q

Anti-dsDNA, anti-Smith

A

SLE

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7
Q

Anti-glutamate decarboxylase

A

Type I diabetes mellitus

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Antihistone

A

Drug-induced lupus

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10
Q

Anti-Jo-1, anti-SRP, anti-Mi-2

A

Polymyositis, dermatomyositis

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11
Q

Antimicrosomal, antithyroglobulin

A

Hashimoto thyroiditis

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12
Q

Antimitochondrial

A

Primary biliary cirrhosis

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13
Q

Antinuclear antibodies

A

SLE, nonspecific

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14
Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Scleroderma (diffuse)

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15
Q

Anti-smooth muscle

A

Autoimmune hepatitis

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16
Q

Anti-SSA, anti-SSB (anti-Ro, anti-La)

A

Sjogren syndrome

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17
Q

Anti-TSH receptor

A

Graves’ disease

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18
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

19
Q

c-ANCA (PR3-ANCA)

A

Granulomatosis with polyangiitis (Wegener)

20
Q

IgA antiendomysial, IgA anti-tissue transglutaminase

A

Celiac disease

21
Q

p-ANCA (MPO-ANCA)

A

Microscopic polyangitis, Churg-Strauss syndrome

22
Q

Rheumatoid factor (antibody, most commonly IgM, specific to IgG Fc region), anti-CCP

A

Rheumatoid arthritis

23
Q

Myasthenia gravis

A

Anti-ACh receptor

24
Q

Goodpasture syndrome

A

Anti-basement membrane

25
Q

SLE, antiphospholipid syndrome

A

Anti-cardiolipin, lupus anticoagulant

26
Q

Limited scleroderma (CREST syndrome)

A

Anticentromere

27
Q

Pemphigus vulgaris

A

Anti-desmoglein

28
Q

SLE

A

Anti-dsDNA, anti-Smith

29
Q

Type I diabetes mellitus

A

Anti-glutamate decarboxylase

30
Q

Bullous pemphigoid

A

Anti-hemidesmosome

31
Q

Drug-induced lupus

A

Antihistone

32
Q

Polymyositis, dermatomyositis

A

Anti-Jo-1, anti-SRP, anti-Mi-2

33
Q

Hashimoto thyroiditis

A

Antimicrosomal, antithyroglobulin

34
Q

Primary biliary cirrhosis

A

Antimitochondrial

35
Q

SLE, nonspecific

A

Antinuclear antibodies

36
Q

Scleroderma (diffuse)

A

Anti-Scl-70 (anti-DNA topoisomerase I)

37
Q

Autoimmune hepatitis

A

Anti-smooth muscle

38
Q

Sjogren syndrome

A

Anti-SSA, anti-SSB (anti-Ro, anti-La)

39
Q

Graves’ disease

A

Anti-TSH receptor

40
Q

Mixed connective tissue disease

A

Anti-U1 RNP (ribonucleoprotein)

41
Q

Granulomatosis with polyangitis (Wegener)

A

c-ANCA (PR3-ANCA)

42
Q

Celiac disease

A

IgA antiendomysial, IgA anti-tissue transglutaminase

43
Q

Microscopic polyangiitis, Churg-Strauss syndrome

A

p-ANCA (MPO-ANCA)

44
Q

Rheumatoid arthritis

A

Rheumatoid factor (IgM AB vs. IgG Fc region), anti-CCP

USMLE (38 decks)

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