Autoantibodies Flashcards by Abby Frederickson

Q

Anti-ACh receptor

A

Myasthenia gravis

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Q

Anti-basement membrane

A

Goodpasture syndrome

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Q

Anti-cardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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Q

Anticentromere

A

Limited scleroderma (CREST syndrome)

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Q

Anti-desmoglein

A

Pemphigus vulgaris

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Q

Anti-dsDNA, anti-Smith

A

SLE

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Q

Anti-glutamate decarboxylase

A

Type I diabetes mellitus

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Q

Anti-hemidesmosome

A

Bullous pemphigoid

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Q

Antihistone

A

Drug-induced lupus

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Q

Anti-Jo-1, anti-SRP, anti-Mi-2

A

Polymyositis, dermatomyositis

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Q

Antimicrosomal, antithyroglobulin

A

Hashimoto thyroiditis

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Q

Antimitochondrial

A

Primary biliary cirrhosis

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Q

Antinuclear antibodies

A

SLE, nonspecific

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Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Scleroderma (diffuse)

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Q

Anti-smooth muscle

A

Autoimmune hepatitis

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Q

Anti-SSA, anti-SSB (anti-Ro, anti-La)

A

Sjogren syndrome

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Q

Anti-TSH receptor

A

Graves’ disease

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Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

Q

c-ANCA (PR3-ANCA)

A

Granulomatosis with polyangiitis (Wegener)

Q

IgA antiendomysial, IgA anti-tissue transglutaminase

A

Celiac disease

Q

p-ANCA (MPO-ANCA)

A

Microscopic polyangitis, Churg-Strauss syndrome

Q

Rheumatoid factor (antibody, most commonly IgM, specific to IgG Fc region), anti-CCP

A

Rheumatoid arthritis

Q

Myasthenia gravis

A

Anti-ACh receptor

Q

Goodpasture syndrome

A

Anti-basement membrane

SLE, antiphospholipid syndrome

Anti-cardiolipin, lupus anticoagulant

Limited scleroderma (CREST syndrome)

Anticentromere

Pemphigus vulgaris

Anti-desmoglein

SLE

Anti-dsDNA, anti-Smith

Type I diabetes mellitus

Anti-glutamate decarboxylase

Bullous pemphigoid

Anti-hemidesmosome

Drug-induced lupus

Antihistone

Polymyositis, dermatomyositis

Anti-Jo-1, anti-SRP, anti-Mi-2

Hashimoto thyroiditis

Antimicrosomal, antithyroglobulin

Primary biliary cirrhosis

Antimitochondrial

SLE, nonspecific

Antinuclear antibodies

Scleroderma (diffuse)

Anti-Scl-70 (anti-DNA topoisomerase I)

Autoimmune hepatitis

Anti-smooth muscle

Sjogren syndrome

Anti-SSA, anti-SSB (anti-Ro, anti-La)

Graves' disease

Anti-TSH receptor

Mixed connective tissue disease

Anti-U1 RNP (ribonucleoprotein)

Granulomatosis with polyangitis (Wegener)

c-ANCA (PR3-ANCA)

Celiac disease

IgA antiendomysial, IgA anti-tissue transglutaminase

Microscopic polyangiitis, Churg-Strauss syndrome

p-ANCA (MPO-ANCA)

Rheumatoid arthritis

Rheumatoid factor (IgM AB vs. IgG Fc region), anti-CCP