Atropine Flashcards

1
Q

Class

A

Muscarinic receptor

antagonist

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2
Q

Actions

A
Inhibits secretions
Tachycardia
Relaxes smooth
muscle
Antiemetic
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3
Q

Mechanism of action

A

Competitive reversible
antagonism at all
muscarinic receptors

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4
Q

Clinical use

A
Pupil dilation for eye
examination
Urinary incontinence
IBD
Antidote for
anticholinesterase
poisoning
Treatment for cardiac
slowing
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5
Q

Adverse effects

A
Constipation
Reduucing
sweating
Dry mouth
Urinary retention
Blurred vision
Raised intraocular
pressure
CNS excitement
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6
Q

where does Atropine bind to and what does it do to it

A

the muscarinic acetylcholine receptor and it inhibits it

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7
Q

in adequate does what does atropine do?

A
  • abolish various types of reflex vagal cardiac slowing or asystole
  • prevents or abolishes bradycardia or asystole produced by injection of choline esters, anticholinesterase agents or other parasympathomimetic drugs
  • cardiac arrest produced by stimulation of the vagus.
  • may also lessen the degree of partial heart block when vagal activity is an etiologic factor.
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