Atrial Fib Flashcards
How does thyroid hormone cause a fib?
Its effects in ion currents of atrial myocytes contribute to genesis of AFib. Causing shortening of AP duration resulting in a substrate for AFib
What are the two causative elements introduce that increase the risk of AFib?
Atrial structure
Electrical abnormalities
What are atrial structure changes that increase the risk of atrial fibrillation?
Fibrosis, dilation, ischemia, infiltration, hypertrophy
What are electrical abnormalities that increase the risk of AFib?
Increased heterogeneity, lower conduction, shorter AP, increase automaticity, abnormal Ca movement
What are the primary contributors to AFib?
Atrial tachycardia remodelling and RAAS activation