Atrial Fib Flashcards

1
Q

How does thyroid hormone cause a fib?

A

Its effects in ion currents of atrial myocytes contribute to genesis of AFib. Causing shortening of AP duration resulting in a substrate for AFib

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2
Q

What are the two causative elements introduce that increase the risk of AFib?

A

Atrial structure
Electrical abnormalities

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3
Q

What are atrial structure changes that increase the risk of atrial fibrillation?

A

Fibrosis, dilation, ischemia, infiltration, hypertrophy

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4
Q

What are electrical abnormalities that increase the risk of AFib?

A

Increased heterogeneity, lower conduction, shorter AP, increase automaticity, abnormal Ca movement

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5
Q

What are the primary contributors to AFib?

A

Atrial tachycardia remodelling and RAAS activation

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