antiarrhythmias class III: K channel blockers

Question 1

What is the cutaneous toxicity of amiodarone?

Answer 1

photosensitivity

Question 2

What is the respiratory toxicity of amiodarone?

Answer 2

pulmonary fibrosis

Question 3

Amiodarone blocks both ______________________ channels.

Answer 3

potassium and inactivated sodium

Question 4

What is the effect of amiodarone on the QT interval?

Answer 4

marked prolongation

Question 5

What is a class III anti-arrhythmic that also has class I, II and IV effects due to its membrane alterations?

Answer 5

amiodarone

Question 6

What microdeposits are a common side effect of amiodarone?

Answer 6

corneal

Question 7

What is a common hormonal side effect of amiodarone?

Answer 7

Hypo or hyperthyroidism

Question 8

The most effective antiarrhythmic for tachyarrhythmias is?

Answer 8

amiodarone

Question 9

What is the first choice drug in the prophylaxis of V-fib?

Answer 9

amiodarone

Question 10

Sotalol and ____________ are class III antiarrhythmics that are typically used in treating life-threatening ventricular arrhythmias but carry a risk of QT prolongation.

Answer 10

amiodarone (used in ventricular tachycardia)

• it is 40% iodine by weight.
  *associated with hepatotoxicity, constipation and neurological effects

Question 11

What anti-arrhythmic causes pulmonary fibrosis due to its ability to covalently bind to tissue proteins at the lung?

Answer 11

amiodarone

Question 12

Which class III antiarrhythmic that requires frequent pulmonary, liver and thyroid functions tests?

Answer 12

amiodarone