Asthma and COPD

Question 1

2 anticholinergics

Answer 1

ipratropium bromide
tiotropium bromide

Question 2

5 corticosteroids

Answer 2

beclomethasone
budesonide
fluticasone
oral prednisone
IV methylprednisolone

Question 3

4 beta agonists (-terol)

Answer 3

albuterol
levalbterol
salmeterol
formoterol

Question 4

1 phosphodiesterase-5 inhibitors

Answer 4

roflumilast

Question 5

2 Leukotriene receptor agonists

Answer 5

montelukast
zafirlukast

Question 6

1 5-lipoxygenase inhibitor

Answer 6

zileuton

Question 7

Anticholinergic MOA

Answer 7

block muscarinic receptors, reducing bronchoconstriction

Question 8

Anticholinergic SE

Answer 8

dry mouth, cough, urinary retention

Question 9

Corticosteroids MOA

Answer 9

anti-inflam; reduce airway inflam

Question 10

Corticosteroids SE

Answer 10

oral thrush, hoarseness, cough, potential reduced bone density

Question 11

Beta-2 agonists MOA (short and long acting)

Answer 11

Short: activate beta-2 receptors to relax bronchial smooth muscles

Long: same as short but with prolonged action

Question 12

Beta-2 agonists SE

Answer 12

Tachycardia, palpitations, tremors, nervousness

Long acting are less frequent

Question 13

Phosphodiesterase-5 Inhibitors MOA

Answer 13

reduces inflam by inhibiting phosphodiesterase-4 enzyme; reduces risk of exacerbations in severe COPD

Question 14

Phosphodiesterase-5 Inhibitors SE

Answer 14

diarrhea, weight loss, nausea, headache, insomnia

Question 15

leukotriene receptor agonists MOA

Answer 15

block leukotriene receptors (antagonists)

Question 16

leukotriene receptor agonists SE

Answer 16

headache, upset stomach, mood changes (montelukast)

Question 17

5-lipoxygenase inhibitor MOA

Answer 17

inhibit enzyme 5-lipoxygenase

Question 18

5-lipoxygenase inhibitor SE

Answer 18

headache, upset stomach, elevated liver enzymes

Question 19

What two techniques/strats can help pts complete activities

Answer 19

pacing and energy conservation

Question 20

What are the 3 signs of impending exacerbation

Answer 20

increased wheezing, breathlessness, acc mus use)