Aspirin Flashcards

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1
Q

What is the mechanism of action of Aspirin?

A

●Non-steriodal anti-inflammatory drug (NSAID).
●Has antiplatelet, antipyretic, anti-inflammatory, analgesic effects. Only given by ambulance personnel for Antiplatelet activity.
●Inhibits (blocks) the enzyme clycooxgenase which results in a reduction of the formation of prostaglandins and thromboxane.

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2
Q

What are the indications for Aspirin?

A

●Myocardial Ischaemia.
●STEMI.

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3
Q

What are the contraindications of Aspirin?

A

●Known severe allergy.
●Third trimester of pregnancy.

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4
Q

What are the cautions for Aspirin?

A

●Known bleeding disorder (will increase risk of bleeding.)
●Clinically significant bleeding.
●Known worsening of bronchospasm with NSAIDs.

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5
Q

What is the adult dose of Aspirin?

A

●300mg once

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6
Q

What are the side effects of Aspirin?

A

●Increased bleeding.
●GI ulcers or bleed (associated with long term use.)

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