artha deck1 Flashcards
Pharm for reducing ETOH effects
Naltrexone or Disulfiram (makes you feel worse/crap with ETOH)
Pharm to reduce ETOH cravings
Acamprosate
Post viral URTI with vertigo, hearing loss and tinnitus
Labyrinthitis
Post viral URTI with vertigo, NO hearing loss and tinnitus
vestibular neuronitis
Investigation for accoustic neuroma
MRI with gadolinium contrast
“What bld test to test annually in Down’s?”
TSH
How long to avoid sexual intercourse post AMI?
8 weeks
COCP medication components
ethinyloestradiol 30mcg levonorgesterol 150mcg
Mirena IUD medication component
Levonorgesterol 52mg
“3 Cx’s of haemachromatosis (systems)”
- CLD - Heart failure (restrictive) - Arthritis (hands)
Gonorrhoea pharm Mx
500mg ceftriaxone IM + 1g azithromycin PO stat
Gonorrhoea contact tracing
2 months
Chlamydia test of re-infection
3 months
Chlamydia test of cure
4 weeks - pregnant or rectal chlamydia
Chlamydia pharm Rx
100mg doxycycline bd 7 days 1g azithromycin stat (pregnant)
Chlamydia contact tracing
6 months
Which anti-HTN can inc risk of T2DM
Thiazides
Which anti HTN causes HIGH calcium
Thiazides
Which anti HTN causes LOW calcium
Loop diuretics (Frusemide)
ICS example name and dose
Fluticasone proprionate 50mcg - child 125mcg - adult
SABA name and dose
salbutamol 100mcg
ICS/LABA name + dose
fluticasone proprionate 50 - 250mcg salmeterol 25mcg
LAMA name + dose
tiotropium 5mcg (respimat) daily
Metformin eGFR contraindication
<30
SGLT2 eGFR contraindication
<45
DPP4 eGFR contraindication
NONE, just dose adjustment (except linagliptin - no change)
Sulphonylureas eGFR contraindication
<30
Metformin eGFR reduce dose to 1g?
30-60
GLP1 agonist dose
dulaglutide 1.5mg weekly
Sulphonylurea + dose
Gliclazide 40mg daily
DPP4-i dose
Linagliptin 5mg
SGLT2 and dose
Empagliflozin 10mg daily
Shockable rhythms
V Fib, V tach
Shockable rhythms pharmacology
Adrenaline 1mg after 2nd shock Amiodarone 300mg after 3rd shock
Non-Shockable rhythms pharmacology
Adrenaline 1mg now, and then every 2nd cycle
“4 H’s of collapse”
Hypoxia Hypovolaemia Hyper/hypokalaemia/metabolic disorders Hypothermia
“4 T’s of collapse”
Toxins Tension pneumothorax Thrombosis Tamponade
AMI - GTN dose
300-600mcg sublingual every 5minsAlways check BP and avoid in inferior AMI
Indications for warfarin for AF Mx
eGFR <30 Valvular AF (mitral stenosis or mechanical valve)
NOAC dose for AF
Apixaban 5mg bd 2.5mg if At least 2 of: - 80+ years old - Weight under 60kg - Creatine over 133
Contraindications to NOAC and warfarin (3)
- Previous intracranial bleed - Recent GI bleed - Pregnancy
Heart rate aim in AF
<80
Beta blocker dose in AF
Atenolol 25mg daily
Post AMI driving abstinence duration
2 weeks (private licence)
Post TIA driving abstinence duration
2 weeks (private licence)
Post CABG driving abstinence duration
4 weeks (private)
Post stroke driving abstinence duration
4 weeks (private)
2nd degree Type I ECG
Gradually elongating PR until drop (Wenkebach)
2nd degree Type II ECG
PR interval is normal Sudden drop in QRSUrgent cardio referral
CCF - Moderate on exertion (Class)?
Clas III
CCF - Mild on exertion (Class)?
Class II
CCF - Symptoms at rest (Class)?
Class IV
CCF - No symptoms (Class)?
Class I
BNP level for CCF
BNP >1800
LVEF <35% medication
Ivabradine
LVEF <40% medication
ANRI - Entresto
Heart Failure Medications + Dose (3)
- Perindopril 2.5mg daily 2. Spironolactone 25mg daily 3. Bisoprolol 1.25mg daily (2nd line if euvolaemic)
HOCM ECG criteria
Deep R waves anterior leads Tall Q waves lateral leads
Diabetic retinopathy medication and dose
Fenofibrate 145mg daily
Tamponade triad
“Beck’s”- Low BP- Muffled heart sounds, Jugular venous distension
Pericarditis meds + dose
Colchicine 500mcg (bd if >70kg, daily if <70kg) for 3 months
Acute Rheumatic Fever meds + dose
Benzathine benzylpenicillin IM as a single dose 1.2 million units (adults)
Groin Rash DDx (4)
Candida Intertrigo Tinea Cruris Flexural Psoriasis Erythrasma
PMHX Melanoma skin checks frequency
- 3 monthly for 2 years - 6 monthly for 2 years- 12 monthly for lifetime
Cat Scratch Disease Rx
Azithromycin 500mg 1st day, 250mg daily for next 4 days
Chickenpox Rx - adults
Adults - Valaciclovir 1g tds 7 days
Chilblains Rx
Keep warm DO NOT RUB/MASSAGE If extensive or painful:- Strong topical steroid +/- occlusive dressing (betamethasone dipropionate 0.05% ointment bd)OR Severe/recurrent:- GTN spray- Nifedipine MR 20mg daily
Which infection is linked with Erythema Multiforme?
Herpes Simplex Virus
Commonest KNOWN cause of Erythema Nodusum
Sarcoidosis
4 causes of LVH
- HOCM - HTN - Atrial regurg - Mitral regurg - Coarctation aorta
Actinic/Solar Keratosis Mx
Spot area = Cryotherapy or Shave + curettageLarge area = Imiquimod 5% 3xweekly for 4 weeks or Fluorouracil 5% daily for 3-4 weeks
Keratocanthoma Rx
3-5 excisional biopsy
SCC Ix
Punch biopsy
BCC Ix
Punch biopsy
SCC Rx
Superficial = Cryotherapy, shave+curettage, Imiquimod 5% 5xweekly for 6 weeksFluorouracil 5% daily for 3-4 weeks3D = surgical excision 3-5mm
Melanoma Ix
Excisional biopsy 2mm
Melanoma Rx
WLE + melanoma unit referral
BCC Rx
Superficial = Cryotherapy - double freeze thaw, shave+curettage, Imiquimod 5% 5xweekly for 6 weeksFluorouracil 5% daily for 3-4 weeks3D = surgical excision 3-5mm
BCC typical spread
Locally
SCC typical spread
Lymphatics
Causes of acne flares (4)
- PCOS- Humidity- Occlusive cosmetics- Drugs - steroids
What features to examine when assessing for a burn? (4)
ColourBlistersSensationCap Refill
Deep dermal burn signs?
PainlessNon-blanchingWhite/mottled skinProlonged cap refill
Satellite lesions in skin folds
Candida Intertrigo
Candida intertrigo Rx
Clotrimazole 1% cream daily
Erysipelas pathogen
strep pyogenes
Chondrodermatitis nodularis Rx
Nitroglycerin ointment bd (1–2% glyceryl trinitrate)
1st line pharm to increase breastmilk supply
Domperidone
Compression mmHg to bandage ulcers
40mmHg
Secondary causes of hyperlipidemia (4)
CKDHypothyroidismT2DMCLD
4 contraindications to stress echo
Unstable anginaSevere aortic stenosisNew LBBBUncontrolled arrhythmia
Lateral STEMI leads + supply
I, AVL, V5, V6Left Circumflex artery
Inferior STEMI leads + supply
II, III, AVFRight Coronary Artery
Anterior STEMI leads + supply
V3-V4Left Anterior Descending
Septal STEMI leads + supply
V1-V2Left Anterior Descending
Posterior STEMI leads + supply
V7-V9Right Coronary Artery
Contraindications to performing Valsalva’s for SVT (4)
AMIHaemodynamic instabilityAortic stenosisGlaucoma
Takotsubo Cardiomyopathy Rx
ACEi or beta blockers until resolved systolic dysfunction ~ 1 month
Dandruff 1st line Rx
Selenium sulphide shampoo
Discoid Eczema Rx
Strong steroid (betamethasone diproprionate 0.05% daily for 2 weeks)
What disease is dermatitis herpetiformis linked with?
Coeliac disease
Dermatofibroma distinctive features (2)
Pale centrePinch sign (central dimple)
Rash with target lesions
Erythema Multiforme
Treatment of Erythema Multiforme
Treat Cause, but otherwise self resolves- Aciclovir for HSV- ABx for mycoplasma pneumoniae
ASTI smoking screening age
12
ATSI fasting lipids, CVD check age
35
ATSI BP, UEC check age
18
Coral pink fluorescence under wood lamp
Erythrasma
Erythrasma Rx
Fusidate sodium 2% ointment bd for 14 days
Red swollen fingers+toes, linked with T2DM
Erythromelalgia
Itch/pain/burning rash in sun-exposed skin
Exercise-induced vasculitis or Golfer’s vasculitis
Exercise-induced vasculitis or Golfer’s vasculitis Rx
Self-resolving in 3-4 weeks
Folliculitis causative pathogens
Bacterial - Staph aureus, Pseudomonas aeruginosaFungi
Folliculitis Rx
Treat according to swab MCS- commonly - flucloxacillin or cephalexin 500mg QID
Rash with firm papules “string of pearls” ring
Granuloma Annulare
Granuloma Annulare associated conditions (3)
T2DMHyperlipidemiaAutoimmune Thyroiditis (children)
Granuloma Annulare Rx
Strong steroid (betamethasone diproprionate 0.05% daily for 2 weeks)
Grover’s Disease Rx
Strong steroid (betamethasone diproprionate 0.05% daily for 2 weeks)
Spotty itchy rash in children (trunk) sparing hands/feet?
Guttate psoriasis- linked with strep infection
Telogen Effluvium triad
- Stressful event- 2-3 months to diffuse hair loss- white bulbs(Pull test = hair coming out)
Hair loss with chemo/radiotherapy
Anagen Effluvium
Exclamation mark hairs
Alopecia Areata
Androgenetic Alopecia Rx
- Minoxidil to dry scalp - for 12+ months (not for females)- Finasteride for 2+ years - halts balding process (SE gynaecomastia)
What virus is associated with Hand, Foot & Mouth Disease?
Coxsackie virus
Management of Hand Foot & Mouth (2)
- Supportive, fluids (can become dehydrated)- Keep home until blistered have dried/crusted
Herpes Simplex Virus Type I management?
First sensation - Aciclovir 5% cream 5 times daily for 5 daysSevere - Aciclovir 400mg tds for 5 days
Post-herpetic Neuralgia Rx (3)
- Simple analgesia/Ice massage2. Lidocaine 5% patch, 3. Amitriptyline 10–25 mg nocteGabapentin 300 mg nocte
Shingles Rx
Valaciclovir 1g tds for 7 days
Impetigo NON-PHARM Rx
- Keep away until 24hrs after starting Abx- Cover wounds
Impetigo Rx (non-endemic) + multiple sores
- Flucloxacillin 12.5 mg/kg up to 500mg QID 7 days. - Keep away until 24hrs after starting Abx
Impetigo Rx (Endemic)
- Benzathine benzylpenicillin IM 1.2 million units- Keep away until 24hrs after starting Abx
Impetigo Rx (non-endemic) + localised sores (3)
- Mupirocin 2% ointment tds for 5 days
Impetigo Rx (penicillin allergy)
- Trimethoprim + sulfamethoxazole, bd for 3 days - child 4/20mg/kg up to 160/800mg
Bullous Impetigo pathogen
Staph aureus (infectious!)
Bullous Impetigo Rx
- Flucloxacillin 500mg QID for 7 days- Do not share towels with other family members
Keratosis Pilaris Rx
- Topical retinoids, salicyclic acid
Lichen Planus Rx
- Symptomatic - potent steroid (beta. dip 0.05%)- Otherwise resolves in a few months
Molluscum Contagiosum causative pathogen
Pox virus
Nappy rash Rx
Dependent on causehydrocortisone 1% + nystatin 100 000 units BD or clotrimazole
Molluscum Contagiosum Rx
Self Resolves
Nappy rash causes (3)
Irritant dermatitisCandidaSeborrheic dermatitisPsoriasis
Nappy rash Rx
Dependent on causehydrocortisone 1% + nystatin 100 000 units BD
Lump with buttonhold invagination when pressed?
Neurofibroma
Perioral dermatitis Rx
Doxycycline 100mg daily for 8 weeks
Tiny black pits in soles of feet (Pitted Keratolysis) Rx?
Clindamycin 1% bd for 10 days
Pityriasis Rosacea Rx?
- Self-limiting - 6-8 weeks- Use corticosteroid cream for itch
Pityriasis Versicolor Rx (2)
selenium sulfide shampoo 2.5% for 10 days OR antifungal creamsApply to wet skin and leave on for 10 minsIf ineffective, flucanozole 400mg oral stat
Pyogenic Granuloma Rx (1)
Imiquimod 5% 5xweekly for 6 weeks vs excision
Rosacea Non-pharm Rx (4)
Cleanser + moisturising routineSPF 30+Trigger avoidanceAvoid perfumes/colognes
Rosacea Pharm Rx (3)
- Topical metronidazole2. Azelaic acid3. Doxy 100mg daily 8 weeks
Scabies Rx
Permethrin 5% cream from jawline downwards overnightRepeat in 1 week
Scarlet fever causative pathogen
Strep Pyogenes
Lace-like/sandpaper rash
Scarlet Fever
Scarlet Fever Rx
Phenoxymethylpenicillin 500mg bd for 10 days
Seborrhoeic Dermatitis (infants) Rx
Salicylic acid 2% + LPC (liquor picis carbonis = coal tar solution) 2% + sulfur 2%
Which tinea locations need oral terbinafine?What dose?
Scalp, nails or widespread250mg oral terbinafine dailyToenails = 12 weeksFingernails = 6 weeks
Which tinea locations need topical terbinafine?
Everywhere except scalp/nails1% terbinafine cream bd 2 weeks
Venous Ulcer appearance
Ragged edge, slight pain, slough
Arterial Ulcer Appearance
Punched out, Pain +++, Cold. Relieved by hanging out of bed
Lump with buttonhold invagination when pressed?
Neurofibroma
Diabetic/Pressure Ulcer Mx (3)
Clean base with salineRelief of frictionIodosorb ointment/Foam dressing
Pityriasis Rosacea Rx?
- Self-limiting - 6-8 weeks- Use corticosteroid cream for itch
Pityriasis Versicolor Rx
selenium sulfide 2.5% for 10 days Apply to wet skin and leave on for 10 mins
Rosacea Non-pharm Rx (4)
Cleanser + moisturising routineSPF 30+Trigger avoidanceAvoid perfumes/colognes
Rosacea Pharm Rx
- Topical metronidazole2. Doxy 100mg daily 8 weeks
T2DM assessment for low risk asymptomatic patients.
- AUSDRISK >40yo
Scarlet fever causative pathogen
Strep Pyogenes
Lace-like scarlet rash
Scarlet Fever
Scarlet Fever Rx
Phenoxymethylpenicillin 500mg bd for 10 days
Seborrhoeic Dermatitis (infants) Rx
Salicylic acid 2% + LPC (liquor picis carbonis = coal tar solution) 2% + sulfur 2%
Which tinea locations need oral terbinafine?What dose?
Scalp, nails or widespread250mg oral terbinafine dailyToenails = 12 weeksFingernails = 6 weeks
Requirements for HbA1c to diagnose T2DM
> 6.5% on TWO occasions
Causes of low HbA1c
AnaemiaHaemoglobinopathiesCKD
Requirements for OGTT to diagnose T2DM
(EITHER)Fasting >72 hours >11
Neuropathic Ulcer Location
Plantar surface (pressure areas), well demarcated
What to examine for with foot ulcers (3)
- Sensation with 10gm monofilament - Ankle Brachial Index Measurement- Dorsalis Pedis/Posterior Tibialis pulse
T2DM Driving license with insulin
2 yearly license review +/- conditional
Arterial Ulcer Mx
Urgent vascular surgeon review for reperfusion
Diabetic/Pressure Ulcer Mx (3)
Clean base with salineRelief of frictionIodosorb ointment/Foam dressing
Urticaria Rx
Loratadine 10mg daily
Who needs annual screening for T2DM? (FBGL) (2)
PrediabetesATSI
T2DM assessment for low risk asymptomatic patients.
- AUSDRISK >40yo
FBGL intermediate range
5.5-6.9Mx = perform HbA1c or OGTT
HbA1c intermediate range
6.0-6.4% Mx = retest in one year
OGTT results for Impaired glucose tolerance
Fasting: <7 mmol/L2 hour : 7.8 - 11 mmol/L
OGTT results for Impaired fasting glycaemia
Fasting glucose: 6.1-6.92 hour glucose < 7.8
Addison’s Ix
Short Synacthen test ○ Gives synthetic ACTH, should normally increase cortisol ○ In Addison’s (underfunctioning adrenal), there is no increased cortisol - positive test
Requirements for HbA1c to diagnose T2DM
> 6.5% on TWO occasions
Causes of low HbA1c
AnaemiaHaemoglobinopathiesCKD
Requirements for OGTT to diagnose T2DM
(EITHER)Fasting >72 hours >11
OGTT results to Dx GDM
Fasting glucose >5.5 (reduce by 1.5)Two hour glucose >8.0 (reduce by 3.0)
T2DM Driving license with OHA’s
5 yearly license review +/- conditional
T2DM Driving license with insulin
2 yearly license review +/- conditional
Which diabetic patients need conditional licenses (4)
- Severe hypoglycaemia- Acute hyperglycaemia- End-organ damage- Commercial drivers on OHA’s/insulin - specialist review
Pre-exercise BGL range for T2DM
5 - 13.9
How often to check BGL if on insulin or sulfonylureas
30-45 minutes
How long after exercise can you get hypoglycaemia with SU’s/insulin?
48 hours
Fasting BGL aim in T2DM
4-7
2 hour post-prandial BGL aim in T2DM
5-10
Severe hypoglycaemia event, driving restriction
6 weeks until stabilised by specialist