1/12/21 Flashcards
Risk Factors SCC
- elederly males
- oudoor
- smoking
- fair skin, blue eyes - aryan
Clinical features of SCC
Can appear suddenly, grow rapidly OR grow slowly over weeks to months
tender and painful
on sun exposed sites
Management of SCC + review?
excision 3-5mm
review 6 montly for 2 years
When to cease diabetic medication pre-op?
Patients on oral glucose-lowering medication EXCEPT **SGLT2 INHIBITORS** and patients on **injectable GLP-1 RAs**:
- continue medications until day prior to surgery
- withhold medication on the morning of the surgery → DOES NOT matter if on the morning of afternoon list
When to cease beta-blockers pre-op?
Beta-Blockers: Continue up to and including the day of surgery
ACEi management pre-op?
ACE Inhibitors: Continue therapy up to day of surgery and withhold morning dose unless heart failure or poorly controlled HTN
Diuretics management pre-op?
Diuretics: Continue therapy up to day of surgery but withhold the morning dose (unless fluid balance is difficult to manage)
Factors that impact on apixaban management pre-op?
bleeding risk and renal function
if apixaban, low risk + normal crc
cease 24hours prior
if apixaban, low risk + low CRC
cease 48 horus prior
if apixaban, high risk + normal Crc
cease 48-72 hours prior
if apixavan, high risk nad low crc
cease 72 hours prior
Causes of Psychosis
- Functional Psychosis → schizophrenia, schizoaffective disorder, schizophreniform disorder, bipolar mood disorder
- Drug Induced Psychosis → amphetamines, hallucinogens, cannabis
- Organic → temporal lobe epilepsy, CNS infections (HIV), Brain Tumours, Thyrotoxicosis, CVD, Wilsons Disease, SLE, head injury
- Other - delusional disorder
Investigations for first episode psychosis
- FBE, UEC
- CMP
- LFTs
- BGL
- TFT
- Urine Toxicology
- Inflammatory Markers
- ECG
- CT Brain
Investigations or examinations to monitor once started anti-psychotic therapy?
- BP + HR
- BMI + waist circumference
- BGL + HbA1c
- Lipid + TGs
- FBC
- PROLACTIN → many antipsychotics can cause dose-dependent hyperprolactinaemia
- can cause infertility, sexual difficulties, gynaecomastia, galactorrhoea, menstrual disturbance, erectile dysfunction and pubertal delay
- ECG
History questions to establish psychosis and cause of psychosis
Anxiety, Elevated or Down Mood, Hallucinations, Delusions - guilt, grandeur, control, reference, Thought - insertion, withdrawal, broadcasting, echo
Self-Harm/Suicide
Illicit Substances
FHx of psychotic disorders or schizophrenia
Examination of Female Urinary Incontinence
BMI + Waist Circumference
Abdominal Examination
Pelvic Examination - prolapse, pelvic floor, atrophic vaginitis
Rectal Examination
Neurological Examination - LL weakness, decreased reflexes or decreased tone
Urine Dipstick - leukocytes, nitrates, blood
Fingerprick BSL
Leakage of Urine on Coughing or Straining
Non-Pharmacological Management of Female Urinary Incontinence.***
- Water → 6-8 cups of fluid a day, reduce fluids after the evening meals
- Caffiene and Alcohol → eliminate caffeiene, fizzy drinks + alcohol can worsen symptoms
- Fibre → avoid constipation, maintait soft bowel motions
- Physical Activity → 30mins of exercise most day of the week. Avoid fitness activities that cause bladder leakage
- Maintain BMI between 18.5-24.9
- Pelvic Floor Exercises
- Avoid lifting - can weaken pelvic floor
- Toilet Habits → empty bladder with urge, do not strain to empty bladder
- Bladder Training → referral to continence nurse or pelvic floor physiotherapist
- Continence pads or accessories - increase QoL
Causes of Urinary Incontienence
Pelvic Organ Prolapse, Weak Pelvic Floor Muscles, Intrinsic Sphincteric Deficiency, Urethral Hyper-mobility
Overactive Bladder Syndrome
Bladder Outlet Obstruction - fibroids, advanced Ca
UTI
Cancer
Constipation
Diabetes
Vaginal Atrophy