30/11/21 Flashcards

1
Q

Clinical Features of Cystic Fibrosis?

A
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2
Q

Diagnosis of Cystic Fibrosis?

A

Screening for immunoreactive trypsin and trypsinogen in newborns detects 75%

Sweat test for elevated chloride and sodium levels

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3
Q

Risk Factors for Suicide?

A

Psychiatric Disorder → especially major depression, bipolar disorder, schizophrenia, schizoaffective disorder, substance use disorder, personality disorder

Current Psychosis

Family History of Suicide

Access to Means of Suicide with high potential lethality → guns, firearms, ropes, hosepipes

Definite plan of suicide attempt

History of dangerous behaviour on impulse

Low likelihood of suicide attempt being detected

Ambivalence toward survival of suicide attempt

Social isolation or absence of social supports

Chronic Medical Illness → especially if painful

Recent Major Loss → includes loss of face in some cultures

Feeling of Hopelessness

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4
Q

Severe Acute Asthma Management

A

Salbutamol (100microg/actuation) via pMDI plus spacer

  • 1-5yo → 6 puffs
  • 6yo → 12 puffs

Ipratropium Bromide (21microg/acutation) via pMDI plus spacer

  • 1-5 yo → 4 puffs
  • 6yo → 8 puffs

Repeat dose every 20-30mins as required for the first hour if needed (or sooner as needed)

Start O2 → titrate O2 >95%

  • If no improvement (within minutes) → for transfer from non-acute settings to ED

Prednisolone (within 1st hour if no improvement or worsening symptoms) → 1mg/kg for 3-5 days

  • in children 1-5yo → if mild/moderate wheezing responds to bronchodilator therapy → avoid systemic corticosteroids
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5
Q

Reaction following MMR vaccine?

A

MMR Vaccine - develop fever 7-10 days after vaccination → can last 2-3 days

fever can be associated with malaise and non-infectious rash

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6
Q

Lithium is associated with ______ diease? Explain what needs to be done.

A

lithium inhibit release thyroid T4 and T3

lithium can cause goitre and hypothyroidism

if thyroid function abnormal → still give lithium but thyroid dysfunction should be treated

TSH and AntiTPO antibody titres should be conducted prior to lithium treatment commencement

TFTs shold be reevaluated every 6-12 months for several years.

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7
Q

Investigations when on lithium?

A

Serum Lithium Concentration - 3-6 months

Serum Creatinine and Urea Concentrations - 3-6 months

Serum Sodium Concentration - assess hydration, assess hypernatraemia in patients with altered conscious state, review every 6-12 hours

TFTs - 6-12 months

Serum Calcium - 12 months

ECG

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8
Q

Signs of mild, moderate and severe dehydration in a child?

A

Mild: No Clinical Signs, Increased Thirst

Moderate: Delayed CRT >2 seconds, Increased RR, Decreased Tissue Turgor

Severe: Very delayed CRT >3 seconds, Increased RR, Signs of Shock, Mottled Skin, Deep Acidotic Breathing

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9
Q

Rabies Exposure? When do you need postexposure prophylaxis? what is it?

A

If nibbling of uncovered skin or minor scratches or abrations without beleding or anything more than this.
if less - no prophylaxis
if more - if non-immune for vaccine d0,3,7,14
if more if immune <3months - nothing
if more and if immune >3 monts -> d0 and d3 doses

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10
Q

Inferior FOot pain

A

Plantar Fascia

Calcaneal Fat Pad

PF FP

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11
Q

Posterior Foot Pain

A

Achilles Tendon Insertion

Superficial Calcaneal Bursa

Posterior Impingement of Soft Tissues/Os Trigonum in active people

Calcaneal Apophysitis - Severs Disease

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12
Q

Lateral Foot Pain

A

Lateral Ligaments of the Ankle

Sinus Tarsi

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13
Q

Medial Foot Pain

A

Tibialis Posterior Tendon and Sheath

Tibialis Posterior Insertion and Apophysis in Adolescents

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14
Q

What is a toddler fracture? Who gets it and why?

A

Occult fracture of the lower limb bones

9 months to 3 years

result of new stressors on bone due to recent and increasing ambulation

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15
Q

Clinical Features and Treatment of Toddlers Fracture?

A

Clinical Features

  • vague symptoms
  • refuse to weight bear
  • irritable

No treatment and spontaneously heal

can have a backslab → fracture clinic in 2 weeks with X-ray

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16
Q

Classification of Medical Epicondyle Fracture? How does this change management?

A

If displacement <5mm -> backslab for 3 weeks and then fracture clinic and collar and cuff for 3 weeks

if displacement >5mm -> refer to ortho. if >15mm -> for reduciton and ORIF

17
Q

What is a maisoneuve fracture?

A

Combination of fracture of the proximal fibular together with an unstable ankle injury - widening of the ankle mortise on xray often comprising of ligamentous injury and/or fracture of the medial malleolus.

18
Q

What is a Galeazzi Fracutre Dislocation? What is the management?

A

Galeazzi Fracture-Dislocation → fracture of the distal third of the shaft of the radius with a disruption to the DRUJ

Management - arm should be splinted and refer to ortho

19
Q

What is a Jones Fracture? How do you treat it and why?

A

Fracture at the base of the 5th metatarsal bone

Treatment → prone to non-union

displacement is increased with persistent weight bearting

immobilsiation is important → non-weight bearing cast for 6-8 weeks

20
Q

Clinical Features of Alcohol Intoxication

A

Clinical Features

  • slurred speech, nystagmus, disinhibited behaviour, incoordincation, unsteady gait, memory impiarment, coma, stupor
  • hypotension and tachycardia
  • euphoria at low BAL → ataxia and impaired judgement → nausea and vomiting, confusion → stupor and LOC
21
Q

Investigations in the context of heavy alcohol use?

A
  • LFTs + Albumin
  • FBE
  • INR
  • B12/Folate - nutrition
  • UEC
  • CMP - decreased
  • HbA1c + FBG
  • Serum Ferritin - elevated
22
Q

Alcohol Cessation Medication

A

Naltrexone 50mg PO daily
Disulfiram 100mg PO daily
Acamprosate 666mg TDS

23
Q

Vaccinations at 4 months.

A

RIP
Rotarix
Infarix Hexa
Prevenar13

24
Q

Max age for rotarix virus?

A

24 weeks - 6 months

25
Q

diagnostic criteria of prader-willi syndrome?

A

NEONATAL HYPOTONIA + FEEDING DIFFICULTIES + OBESITY

26
Q

Clinical Features of Prader-Willi Syndrome

A

Perinatal → reduced fetal movements, SGA, polyhydramnios, breech positioning, asymmetrical intrauterine growth

INfancy → hypotonia, feeding difficulties (poor suck → failure to thrive), weak cry + genital hypoplasia

Childhood → Late acquisition of major milestones

Progressive development of obesity

27
Q

Causes of Hypotonia and Weakness in INfancy?

A
  1. Ill infant
  2. Genetic Syndromes - Down syndrome, prader willi, trisomy 18, trisomy 13
  3. Inborn errors of metabolism
  4. Hypothyroidism, hypoglycaemia
  5. Primary muscular disorders - DMD, BMD, Hypoxic Ischaemic Myelopathy
  6. Cerebral palsy
28
Q

Vaccinations at 2 months.

A

Rotarix → Rotavirus

Infarix Hexa → Diptheria, Tetanus, Pertussis, Hepatitis B, Haemophilus Influenzae Type B, Polio

Prevenar 13 (13vPCV) → Pneumococcal

29
Q
A