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First Aid Psychiatry > Antipsychotics > Flashcards

Antipsychotics Flashcards

1
Q

Use of all antipsychotic medication in this group of patients is associated with increased risk of deaths

A

Elderly with dementia-related psychosis

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2
Q

Antipsychotics that repress primarily the positive symptoms of schizophrenia

A

Typical antipsychotics

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3
Q

Primary mechanism of action of typical antipsychotics

A

Inhibits D2 receptors

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4
Q

Common endocrine side effects of all typical

A

Hyperprolactinemia, galactorrhea

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5
Q

Two low potency, typical antipsychotic drugs

A

Chlorpromazine, thioridazine

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6
Q

Typical antipsychotic associated with retinopathy and cardiac toxicity

A

Thioridazine

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7
Q

Common side effects of low potency typical antipsychotic drugs

A

Dry mouth (anticholinergic), sedation (antihistamine), hypotension (α1 block)

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8
Q

Three high potency, typical antipsychotic drugs

A

Haloperidol, fluphenazine, trifluoperazine

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9
Q

Typical antipsychotic that can also be used for Tourette syndrome

A

Haloperidol

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10
Q

Side effects more commonly associated with high potency typical antipsychotic drugs

A

Dystonia, akathisia, bradykinesia, tardive dyskinesia (extrapyramidal symptoms)

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11
Q

Treatment for drug-induced acute extrapyramidal symptoms

A

Benztropine, diphenhydramine

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12
Q

Life-threatening side effect associated with typical antipsychotic drugs

A

Neuroleptic malignant syndrome

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13
Q

Treatment for drug-induced neuroleptic malignant syndrome

A

Dantrolene

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14
Q

Advantage of atypicals over typical antipsychotics

A

Less extrapyramidal symptoms, more effect against negative symptoms of schizophrenia

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15
Q

Primary mechanism of action of atypical antipsychotics

A

Inhibit 5-HT2 receptors

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16
Q

Atypical antipsychotic that can produce potentially fatal agranulocytosis and increase incidence of seizures

A

Clozapine

17
Q

Two atypical antipsychotics that can cause weight gain

A

Clozapine, olanzapine

18
Q

Two atypical antipsychoics that can prolong the QT interval

A

Risperidone, ziprasidone

19
Q

Atypical antipsychotic that can increase prolactin levels and cause gynecomastia and irregular menstruation in men and women, respectively

A

Risperidone

20
Q

Atypical antipsychotic that can also be used to treat irritability in autistic children

A

Aripiprazole

First Aid Psychiatry (12 decks)

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