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Farma 2 > Antihipert > Flashcards

Antihipert Flashcards

1
Q

Fx antagonista Ca

A

Nifedrina
Verapamilo y dieltazen

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2
Q

Canal que actúa los bloq de Ca

A

L

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3
Q

Antg ca
Farmacocinetica
Absorcion
Met
Administración
Unión a proteina

A

Absorcion alta 90-100%
Met hepático, citocromo p450
Adm v.o
Unión a proteina 70-88 %

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4
Q

Cuanto demora en iniciar efecto de antg ca

A

30 a 60 min

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5
Q

Adv antg ca

A

Vasodilatador
Eritema, mareo,cefalea,hipotension

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6
Q

Suspensión brusca de antg de ca en px cardiopatas isquemicos provoca

A

Angina

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7
Q

Antg ca da rubor

A

Nifedipina

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8
Q

Interacción antg ca, aumenten concentración de que

A

Propanodol metroprolol
Fx que se biotransforman en p450

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9
Q

Antg de ca disminuyen que fx

A

Digoxina

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10
Q

Antg de ca unido a cual fx causa hipotension excesiva

A

Verapamilo + quinidina

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11
Q

Uso de antg ca

A

Antihipertensiok
Previene ecv
Angina variable
Arritmia supraventricular
Hipertenso con:epoc,isquemia,asma

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12
Q

Diurético tiazidas donde actuan

A

Tubo contorneado distal y excreta en el proximal

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13
Q

Mecanismo acción diureticos

A

Reabsorbe na y cl

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14
Q

ind terap de tiazidas

A

fallla cardiaca y reducen muerte iam
diabetes insipido
edema

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15
Q

tiazida disminuye E de

A

ca

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16
Q

tiazidas
adm

A

v.o

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17
Q

reac adv tiazidas gastrointestinal

A

anorexia, nauseas, vomito

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18
Q

reac adv tiazidas derma

A

fotosensible eritema cutaneo

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19
Q

interaccion tiazidas disminuye

A

anticoag
unicosurico
insulina

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20
Q

interaccion tiazidas aumenta

A

anestesia, glucosidos digitalicos y litio

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21
Q

beta bloq tx

A

angina de pecho

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22
Q

beta bloq no selec

A

propanolol
sotalol
noladol
timolol

23
Q

beta bloq selec

A

atenolol
esmolol
metroprolol

24
Q

inhibidor enzima convertidora de angiotensina IECA Fx

A

Isonopril
captopril

25
Q

Tx IECA

A

Hipertensión
insuficiencia cardiaca

26
Q

mec accion IECA

A

Impiden transformacion a angiotensina 2

27
Q

reac adv ieca

A

angioedema
neutropenia
hiperpotasemia
hipotension
insuficiencia renal aguda

28
Q

Antagonista de receptor angiotensina FX

A

Lorsartan
Ibersartabn
Valsartan

29
Q

Antagonista de receptor angiotensina Tx

A

Hipertensión
insuficiencia cardiaca

30
Q

Antagonista de receptor angiotensina mec accion

A

antagonozan receptor At1 y disminuye concentracion angiotensina

31
Q

inhibidor renina Fx

A

aliskireno

32
Q

inhibidor renina tx

A

hipertensión

33
Q

toxic inhibidor renina

A

hiperpotasemia
altera renal
teratogenico

34
Q

mecc accion inhibidor renina

A

compite con angiotensinogeno en el sitio de union de la renina
falso sustrato

35
Q

simpaticolitico accion central receptor activa o inhibe

A

activa alfa 2

36
Q

simpaticolitico accion central fx

A

cloridina y metildopa

37
Q

aldonet

A

metildopa

38
Q

simpaticolitico accion central mecc accion

A

disminuye noradrenalina

39
Q

simpaticolitico accion central causa sedacion en reac adv

A

cloridina

40
Q

simpaticolitico accion central causa anemia hemoliticaen reac adv

A

mitildopa

41
Q

antagonistas alfa fx

A

prazosina
terazosina
dexazosina

42
Q

antagonistas alfa mec accion

A

bloquean alfa 1 e impiden vasoconstriccion

43
Q

antagonistas alfa adm

A

v.o

44
Q

minipres

A

prazosicna

45
Q

tlytrin

A

terazosina

46
Q

antagonistas alfa adv

A

hipotesion ortostatica

47
Q

antagonista terminacion simpatica fx

A

GUANETIDINA
RESERPINA

48
Q

antagonista terminacion simpatica mec

A

disminuyen efecto simpativo cardiovascular
al antagonozar las aminas vasculares de los nervios adrenergicos e intervenir en vesicula

49
Q

vasodilatadores

A

verapamilo y dieltazem (bloq no selectivo ca)
nifedipina y alodipina (bloq conducto vesicular ca)

hidralazina emite oxido nitrico

minoxidil abre conducto de k y vasodiatacion

50
Q

antihipertensivo parenteral fx

A

nitroprusiato
diazoxido
labetalol

51
Q

antihipertensivo parenteral mec accion

A

liberan oxido nitrico
abre condulto de k
antag receptor alfa y beta

51
Q

cardibux

A

nitroprusiato

52
Q

antihipertensivo parenteral tx

A

vasodilatador potente
ugercia hipertensiva

52
Q

adv antihipertensivo parenteral

A

hipotension excesiva

Farma 2 (18 decks)

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