Anti-Virals Flashcards
which drug is a pyrimidine nucleoside
trifluridine
what is trifluridine used to treat
herpetic keratitis
what are the adverse effects of trifluridine
discomfort
palpebral edema
which purine nucleoside is topically applied for ocular herpesvirus
vadarabine
what is the main use of vadarabine
acyclovir resistant herpes
true or false:
vidarabine is helpful when treating all resistant herpes
false
it only inhibits DNA viruses
how is vidarabine eliminated from the body
urine
which drugs have better efficacy when phosphorylated to triphosphate
acyclovir
valacyclovir
true or false:
acyclovir and valacyclovir are unable to eliminate latent infections
true
how are acyclovir and valacyclovir eliminated from the body
unchanged by glomerular filtration
true or false:
it is best to give acyclovir and valacyclovir orally
false
low oral bioavailability
what is ribavirin used for in cats
FELV
FIV
calicivirus
coronavirus
what is ribavirin used for in dogs
distemper
parainfluenza
what are the main toxicities with ribavirin
cats - bone marrow
dogs - hepatotoxicity
which drug is not approved for BLV
zidovudine
true or false:
it is fine to give zidovudine orally
true
high oral bioavailability
what species is zidovudine used in
cats
bovine*
what are the adverse effects of using zidovudine in cats
progressive anemia and neutropenia
which drug has a narrow range of activity against viruses but also can be used for pain treatment
amantadine
what is the main indication of use of amantadine
equine influenza
how is amantadine eliminated from the body
unchanged renally
which interferon anti-virl is used for parvo, FIV and FeLV
interferon omega
what is the main use of Type 1 interferon
herpes
calicivirus
stress induced diseases
what species is Type 1 interferon used in
dogs
cats
cattle
pigs
horses
what species is interferon omega used in
dogs
cats
