Anti-Emetics Flashcards
1
Q
Vomiting Center
A
Vomiting center receives input from CTZ as well as peripheral sites via vagus nerve
Opioids inhibit vomiting center at high doses
2
Q
Work on CTZ to decrease N/V
A
Benzos/propofol
Dopamine Antagonists (droperidol, reglan, metoclopimide, haloperidol)
Serotonin Antagonist: zofran, dolasetonr, granisetron
Histamine Antagonist: hydroxyzine, dimenhydrinate, meclizine
Acetylcholine (muscarinic) Antagonist: scopolamine
3
Q
Best approach to managing PONV
A
Multimodal approach
Usually serotonin antagonist and something else
4
Q
Precedex
A
Popular for prevention of PONV
5
Q
Cause QT interval prolongation at high doses
A
Ondansetron
6
Q
Corticosteroids used for N/V
A
Dexemethasone 4 mg
