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Pharm > ANS Medications > Flashcards

ANS Medications Flashcards

1
Q

Phenylephrine

A

PURE ALPHA!

Increase: SBP/DBP/SVR

Decrease: HR d/t reflex bradycardia

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2
Q

Norepinephrine actions

A

alpha, some beta

Increase: HR/BP/SVR… mostly vasoconstriction

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3
Q

Epinephrine actions

A

Beta, some alpha

Increase: SBP/HR

Decrease: DBP/SVR d/t slight vasodilation from b receptors

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4
Q

Dobutamine actions

A

PURE BETA!

Increase: SBP/HR

Decrease: DBP/SVR

Works on heart, vasodilation from b receptors, widened pulse pressure

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5
Q

Dopamine actions

A

Dopamine, beta, alpha

Increase: SBP/HR

Decrease: DBP/SVR…decrease SVR in high doses

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6
Q

Dopamine Dosing Effects

A

Low dose (2-5 mcg): stimulate dopamine receptors mainly in brain and kidney

Medium dose (5-10): B (heart) effects, vasodilates—> shock dose

High dose (10-15): B and A effects

Dopamine—>beta—>alpha

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7
Q

Milrinone MOA

A

PDE III inhibitor: prevent breakdown of second messenger cAMP allowing catecholamine release

Increase: HR/Contractility, vasodilation

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8
Q

Vasopressin Dosing

A

0.04-0.1 units/min

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9
Q

Phenylephrine dosing

A

20-200 mcg/min

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10
Q

Norepinephrine Dosing

A

1-20 mcg/min

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11
Q

Epinephrine Dosing

A

1-20 mcg/min

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12
Q

Dobutamine Dosing

A

1-20 mcg/kg/min

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13
Q

Milrinone Dosing

A

37.5-75 mcg/kg bolus following by 0.375-0.75 mcg/min

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14
Q

Adverse Effects of Dobutamine

A

Tachycardia, dysrhtymias, hypotension

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15
Q

Adverse Effects of Dopamine

A

Tachycardia dysrhythmias, decrease PaO2, mesenteric hypoperfusion, GI motility inhibition, T-cell inhibition

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16
Q

Adverse Effects of Epinephrine

A

Tachycardia, dysrhythmias, decreased PaO2, mesenteric hypoperfusion, increased lactase, hyperglycemia, immunomodulation

17
Q

Adverse Effects of NE

A

Mixed effects on myocardial performance and mesenteric perfusion, peripheral ischemia

18
Q

Adverse Effects of Phenylephrine

A

Mixed effects on myocardial performance, peripheral ischemia

19
Q

Adverse Effects of Vasopressin

A

Mixed effects on myocardial performance, mesenteric hypoperfusion, peripheral ischemia, hyponatremia, thrombocytopenia

20
Q

Ephedrine Action

A

Alpha and beta agonist

Direct (on receptor itself) and indirect (causes release of catecholamines)

Central (pass BBB) and peripheral

***will increase HR

21
Q

Ephedrine dosing

A

5 mg at a time up to …..

Pharm (24 decks)

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