ANATOMY - ventricles and CSF Flashcards

1
Q

3 components of CSF

A

water (mainly)
protein
immunoglobulins

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2
Q

where is 75% of CSF made

A

choroid plexus in the ventricles

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3
Q

where is 25% of CSF made

A

subarachnoid membrane, circumventricular organs

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4
Q

how much CSF is made per day 1

A

500-600ml

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5
Q

what is the vol capacity of CNS (for CSF)

how many times per day does the CSF get replaced then

A

150ml

replaced 3-4 times per day

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6
Q

what is normal CSF pressure

what is high CSF pressure

A

10mmHg

> 15mmHg

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7
Q

what are the first ventricles in the ventricular system

A

lateral ventricles

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8
Q

what shape are the lateral ventricles

A

horn shaped

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9
Q

what ventricle is after the lateral ventricles in the ventricular system

A

3rd ventricle

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10
Q

what ventricle is after the 3rd ventricle in the ventricular system

A

4th ventricle

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11
Q

what foramen is between the lateral and 3rd ventricles

A

interventricular foraminae of munroe (x2 for each lateral ventricle)

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12
Q

what foramen is between the 3rd and 4th ventricles

A

cerebral aqueduct of sylvius

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13
Q

what happens when the CSF reaches each new ventricle

A

new CSF is added, produced by thee choroid plexuses

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14
Q

at which brainstem level is the cerebral aqueduct of sylvius (between the 3rd and 4th ventricles)

A

levels of pons and midbrain

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15
Q

where, in relation to the brain, is the 4th ventricle

A

bottom of cerebellum

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16
Q

where does CSF go after its gotten to the 4th ventricle

A

subarachnoid space
OR
central canal (then subarachnoid space via arachnoid granulations)

17
Q

how does the CSF get from 4th ventricles to subarachnoid space/central canal

A

single median aperture and paired lateral apertures

18
Q

after the CSF ends up in the arachnoid space after going through the full ventricular system, where odes it end up

A

dural venous sinuses

19
Q

how is CSF absorbed into the venous circulation

A

subarachnoid granulations into superior sagittal sinus

20
Q

where does the CSF go after its in the subarachnod space

then where

A

dural venous sinuses

venous blood back to heart

21
Q

what is the function of CSF (2)

A

protects brain by making it ‘float’
exchange of things from brain to blood and vice versa

eg removes metabolites
eg supplies brain with water,, amino acids, ions etc

22
Q

how do you investigate CSF

A

lumbar puncture

23
Q

where are the choroid plexuses

how did this happen embryologically

A

in the walls of ventricles (later, 3rd and 4th)

invagination of ventricle walls = choroid fissure formation