ANATOMY - ventricles and CSF Flashcards
3 components of CSF
water (mainly)
protein
immunoglobulins
where is 75% of CSF made
choroid plexus in the ventricles
where is 25% of CSF made
subarachnoid membrane, circumventricular organs
how much CSF is made per day 1
500-600ml
what is the vol capacity of CNS (for CSF)
how many times per day does the CSF get replaced then
150ml
replaced 3-4 times per day
what is normal CSF pressure
what is high CSF pressure
10mmHg
> 15mmHg
what are the first ventricles in the ventricular system
lateral ventricles
what shape are the lateral ventricles
horn shaped
what ventricle is after the lateral ventricles in the ventricular system
3rd ventricle
what ventricle is after the 3rd ventricle in the ventricular system
4th ventricle
what foramen is between the lateral and 3rd ventricles
interventricular foraminae of munroe (x2 for each lateral ventricle)
what foramen is between the 3rd and 4th ventricles
cerebral aqueduct of sylvius
what happens when the CSF reaches each new ventricle
new CSF is added, produced by thee choroid plexuses
at which brainstem level is the cerebral aqueduct of sylvius (between the 3rd and 4th ventricles)
levels of pons and midbrain
where, in relation to the brain, is the 4th ventricle
bottom of cerebellum
where does CSF go after its gotten to the 4th ventricle
subarachnoid space
OR
central canal (then subarachnoid space via arachnoid granulations)
how does the CSF get from 4th ventricles to subarachnoid space/central canal
single median aperture and paired lateral apertures
after the CSF ends up in the arachnoid space after going through the full ventricular system, where odes it end up
dural venous sinuses
how is CSF absorbed into the venous circulation
subarachnoid granulations into superior sagittal sinus
where does the CSF go after its in the subarachnod space
then where
dural venous sinuses
venous blood back to heart
what is the function of CSF (2)
protects brain by making it ‘float’
exchange of things from brain to blood and vice versa
eg removes metabolites
eg supplies brain with water,, amino acids, ions etc
how do you investigate CSF
lumbar puncture
where are the choroid plexuses
how did this happen embryologically
in the walls of ventricles (later, 3rd and 4th)
invagination of ventricle walls = choroid fissure formation
