anaesthetics Flashcards
who said that it wasn’t the governments job to get involved with social problems
bentham
who said that it was the governments responsibility to get involved with social problems
chadwick
what happened by the year 1899
thousands of volunteers were too sick to serve in the Boer war.
what were some of the biggest changes due to population growth in the 19th century industrial era
by 1851 more people lived in towns than countryside
more people worked in industry than agriculture
industry became richer than landownership
workers were treated badly with long hours for low wages
what was the population in 1801 and 1901 and this was a rise of how much
1801- 16.3 million
1901- 41.6million
increase of 25.3 million
what was Louis Pasteur the first person to do
establish the link between germs and disease.
what was Louis Pasteur known as
the father of microbiology
what did Louis Pasteur argue
that micro organisms were responsible for disease and if only we could discover these microorganisms then a vaccine could be developed to specifically target the disease. He called them germs
what could Louis Pasteur do
develop effective vaccines to target specific diseases
what did Louis Pasteur’s first work on chicken cholera lead to and in what year
his first work on chicken cholera led to an effective vaccine against rabies
what process did louis pasteur invent
pasteurisation
what is the process of pasteurisation
a process which preserved liquids to stop them from spoiling
what was Robert Koch able to do in the laboratory
he was able to link particular germs to particular diseases
in what year did Robert Koch identify the specific bacillus (rod-shaped bacteria) that caused tuberculosis
1882
in what years did Robert Koch identify the specific bacillus (rod-shaped bacteria) responsible for cholera and whose work from which year did this confirm
identified cholera bacillus in 1883 and 1884 confirming the work of John Snow in Britain in 1854
who developed a way to stain bacteria so they were easier to identify under a microscope
Robert Koch
After Koch discovered a way to stain bacteria, him and his students isolated the causes of many diseases such as …..
diptheria, cholera, typhoid, anthrax, pneumonia, plague, tetanus and whooping cough all of which were major killer diseases in Britain
what effective treatment did Paul Erlich discover what was its name when was it discovered and what was it called
Salvarson 606 developed in 1910
was an effective treatment for syphilis
why is it called Salvarsan 606
becasue it was the 606th drug Paul Erlich and his colleagues used to try to kill the germs causing syphalis
salvarson 606 was the first of what
what became known as ‘magic bullets’
what are ‘magic bullets’
carefully designed drugs targeting the specific germs causing that illness and having little or no effect on any other part of the body
what were the number of babies that died before their first birthday in Britain in 1899
142/1000
how many babies died before their first birthday in York
250/1000
what year did the stethoscope become widely used after
1850
when was the first x-ray machine invented
1895
what were held as scientists realising the importance of observation
first clinical trials
from what year onwards was there better knowledge of tropical diseases such as malaria and yellow fever
1850 onwards
how did technology improve medicine
machines were invented to make tablets, sugar coated pills and even gelatine capsules this allowed accurate doses of medicine to be given and themass production of drugs
what was Mrs Beeton’s Book, The book of household management published
1861
what did Mrs Beetons Book recommend everyone should have in their cupboards
recommended that every household should have opium powders and laudanum (90% alcohol, 10% opium) in their cupboards
why was Laudanum often given to children
to help them sleep or to keep them quiet
when did Aspirin go on sale in Britain as an every day painkiller
1899
which chemist began in the 19th century, making medicines
Boots the chemist
What year did Thomas Beecham open his first factory and what did it make
1859 and it made cold powders
what was a major ingredient in some medicines and what did others contain
Alcohol was a major ingredient and some contained arsenic and mercury, both are poisonous
other medicines were addictive and contained large amounts of what
large amounts of cocaine and opium as their active ingredient — very addictive
what were mortality rates before the 19th century during surgeries and what were they down to by the end
before the 19th century mortality rates were as high as 40% during surgeries
by the end of the 19th century they were down to 10%
who came up with nitrous oxide (laughing gas)
Sir Humphrey Davy
who succesfully amputated a leg using ether
Robert Liston
the use of nitrous oxide as a recreational drug became an immediate success in what year
1799
what was nitrous oxide used for
used to relieve pain in operations
when did Sir Humphrey Davy publish his findings about nitrous oxide
1800
what were some problems with nitrous oxide
difficult to control dosage
hard to inhale and caused vomiting
sometimes the patient would wake up during the operation
it could ignite
what were some problems with ether
caused coughs and vomiting
ether was flammable and induced semi-commas
who created chloroform
James Simpson
chloroform was used in which year after James Simpson did what
used in 1847 after experimenting on himself and his friends to reduce pain in childbirth.
what did chloroform cause in patients
dizziness, sleepiness and unconsciousness in patients and needs to be carefully administrated
what anaesthetic did Queen Victoria use in childbirth and in what year
she used chloroform in childbirth in 1853
drawbacks of chloroform
had to be inhaled
people objected to the use of these painkillers as being unnatural
Some surgeons had higher death rates using chloroform so stopped using it in the 1970s
give an example of a death when using chloroform
Hannah Greener died aged 14 when using chloroform in a procedure for an ingrown toenail, chloroform gave heart issues so this could be what happened to her
when were coca leaves from South America used to make cocaine
in the 1850’s
what was cocaine used for
it was dropped into the eyes as a local anaesthetic
when did the use of cocaine as an anaesthetic dramatically increase
after 1891 when it was chemically made
drawbacks of cocaine
had to be given in careful doses
cocaine was addictive
when was cocaine first used
1884
when was nova-cocaine used
1905
what were some downsides to anaesthetics
hard to get the dosage correct and infections were still a problem
what did contagionists believe
believed that infection was spread from contact with infected people
who invited his friends round to his house to inhale gas and which gas was it
Sir Humphrey Davy invited his friends around to his house to inhale nitrous oxide
what was the biggest killer in surgery
sepsis infection an infection caught during an operation
what was sepsis infection also known as
hospital gangrene
Joseph Lister based his findings on experimentation and observation of what
procedures done on frogs
who was the boy that Joseph Lister later based his findings on experimentation and observation of procedures on
a boy called Jamie Greenlees who had a broken leg
who first started using carbolic acid
Joseph Lister
what did Joseph Lister use carbolic acid on
started to use an operating room sterilised with carbolic acid
sterilised instruments with carbolic acid
soaked wounds with carbolic acid
used dressings sterilised with carbolic acid
what did Joseph Lister reduce mortality rates and over what time period
he managed to reduce mortality rates in his operations by 46% to 15% in only 3 years