Anaemia Flashcards
anaemia
reduction in haemoglobin in blood compared to normal values in that population
what blood test can give indication of cause of anaemia
MCV - size of rbcs
why does marrow failure cause anaemia
reduced number of rbc’s therefore less rbcs to package haemoglobin into
why do deficiency states of haematinics cause anaemia
reduced haematinics means reduced rbc’s therefore reduced haemoglobin
Name the 3 main haematinics
iron
vit b12
folate ( folic acid made by manufacturers and converted to folate by body)
where is all forms of iron absorbed by the body
transporter systems in the intestinal cell wall
what form must non heme iron be converted to to be absorbed by the body
2+
what iron is easiest for the body to absorb
heme iron
achlorydia
disease seeing lack of stomach acid therefore non heme 3+ iron cant be converted to 2+
iron food sources
meat and leafy greens
vitamin B12 food sources
milk/dairy and meat
how is vitB12 absorbed by the body
intrinsic factor (secreted by stomach) binds to vitb12 and this complex passes to terminal ileum where it is absorbed via a transporting sytsem
folate food sources
leafy greens, seeds and nuts
during pregnancy what haematinic is recommended to be taken in supplemements
folic acid - deficiences can lead to neural tube defects
thalassemia
inherited condition seeing a mutation to globin chains meaning little to no haemoglobin is produced