An introduction to clinical dermatology Flashcards
A serious drug allergy/ result of infection which results in multiple lesions ranging from minor to major
Erythema multiforme
Tool used to look at pigmented lesions
Dermoscope
Eczema in infants usually
Begins on the face
distribution of psoriasis
Extensor surfaces on limbs
Koeberberisation is associated with
Psoriasis
Koebernerisation =
Lesions along site of trauma
Acronym used to describe individual lesions:
SCAM
SCAM
Size/Shape
Colour
Associated secondary changes
Morphology/Margin
Acronym used for looking at pigmented lesions
ABCDE
ABCDE
Asymmetry Irregular Border two or more Colours Diameter >6mm Evolution of lesion
Score used to grade psoriasis
PASI
Ways lesions can be disributed
- Localised
- Generalised
- Widespread
- Flexural
Ex of places flexural lesions can show:
- groin
- neck
- behind ears
- popliteal fossa
- antecubital fossa
PASI score grades lesions according to:
Redness, thickness, scale of lesions
Photosensitive =
affects sun-exposed areas
Dermatome =
Area of skin supplies by a single spinal nerve.
ex of pressure areas:
sacrum, buttocks, ankles, heals
Lesion =
area of altered skin
Naevus =
localised malformation of tissue structures.
Itching =
Pruritus
Descriptions of colour:
- erythema
- hyper-pigmentation
- melasma
- de-pigmentation
- vitiligo
Petechiae =
small, pinpoint macules
Purpura =
red or purple in colour, bleeding into skin
Ecchymosis =
bruise
3 most common inflammatory dermatoses =
- Acne
- Atopic dermatitis/eczema
- Psoriasis
Acne is most common what age and gender?
age = 12-25 gender = female (earlier puberty)
Areas of acne:
face, back, chest
Clinical features of acne:
- Seborrhoea
- Comedones
- inflammatory lesions
- scarring
Non-inflammatory lesions =
Comedones
Open comedones
Blackhead. Enlarged hair follicle opening filled with melanin.
Closed comedones
Whiteheads. Small, raised, non-inflammaed sport.
Inflammatory lesions found in acne:
papule
pustule
nodule
cyst
Cyst =
papule or nodule that contains fluid
2 types of scarring found in acne:
Atrophic
Hypertrophic
Atrophic scarring
Sunken recess in skin, pitted appearance.
Hypertrophic scarring
overproduction of collagen.
Atopic eczema is a … hypersensitivity
Type 1
Atopic eczema is characterised by:
relapses and remission
Triggers for eczema:
Irritants, environmental triggers (diet, stress)
Clinical presentation of AD:
- Erythematous, dry, scaly
- flexor aspects (popliteal and antecubital fossa)
Chronic scratching in atopic dermatitis can lead to:
Exocoriations and lichenification
Bulla:
large, fluid-filled blister. >0.5 cm in diameter.
Psoriasis is a type … hypersensitivity
Type IV
Most common type of psoriasis:
Chronic plaque psoriasis
Intense and usually widespread reddening of the skin due to inflammatory skin disease:
Erythroderma
Complications of erythroderma:
- secondary infection
- fluid loss, electrolyte imbalance
- hypothermia
- high-output cardiac failure
- capillary leak syndrome
Weals:
transient lesions due to oedema. happen in urticaria
Urticaria is due to significant…
Histamine release in the skin
3 types of skin infections:
- bacterial
- viral
- fungal
Ex bacterial skin infection
Staphlococcal (e.g. cellulitis)
Streptococcal
Ex viral skin infection
varicella zoster
Herpes simplex
HPV
Ex fungal skin infection
Tinea
Candida
Erythrasma
common skin condition, under skin folds.
Organisms causing erythrasma
Corynebacterium minutissimum
Ex of benign tumors:
- warts
- seborrheic keratoses
Warts are due to:
a virus
Types of skin cancer
- Basal cell carcinoma
- Squamous cell carcinoma
- Malignant melanoma
Basal cell skin cancer:
- locally invasive
- rarely metastasises
- slow-growing
Most common malignant skin tumour:
Basal cell skin cancer
Causes of basal cell carcinoma:
UV exposure Hx of severe sunburn in childhood Type 1 skin Male Immunosuppression Hx of previous skin cancer Genetic predisposition
Common sites of basal cell carcinoma:
Head, neck
Causes/risk factors for malignant melanoma:
- Excessive UV exposure
- Type 1 skin
- Hx of multiple moles/atypical moles
- FHx
- Previous Hx of melanoma
Common sites of melanoma
- legs in women
- trunk in men
Measure of depth of lesion, can provide info on prognosis:
Breslow depth (T1-T4)