Amino Acids Flashcards

1
Q

amino acids are the building blocks of ______

A

proteins

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2
Q

proteins are polymers of amino acids linked by a ______

A

peptide bond

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3
Q

a long chain of amino acids formed this way is a _____

A

polypeptide

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4
Q

what are the functions of amino acids?

A

Building blocks of protein, functioning of body, blood clotting, skeletal muscle + skin, locomotory movement, hormones are formed by amino acids, albumin to transport proteins in blood + maintain circulatory system

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5
Q

an amino acid has a _____ group, _______ group, ______ and ______ group

A

amino, carboxylic, hydrogen, and R

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6
Q

how to classify amino acids
- varies species to species

A
  • location
  • acidity
  • phenyl group?
  • occurrence in protein
  • polarity of r group
  • nutrient value
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7
Q

how are amino acids absorbed?

A

active transport by the micro villi/villi of the small intestine

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8
Q

T/F: There is an active transport system for neutral amino acids and one for basic amino acids

A

true

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9
Q

__ Form of amino acids are absorbed preferentially to __ form

A

L;D

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10
Q

Neutral _____ inhibit basic amino acids
Basic ______ inhibit neutral amino acids

A

can; cannot

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11
Q

T/F: some amino acids compete with each other for transport

A

true

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12
Q

what happens after amino acids are absorbed?

A

tissue protein synthesis
synthesis of enzymes, hormones, and other metabolites
deamination or transamination and use of the carbon skeleton for energy

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13
Q

what is deamination?

A

excess amino acids being converted into urea in the liver with enzymes to maintain homeostasis

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14
Q

How are proteins synthesized and degraded?

A

presence of nucleic acids required for protein synthesis, DNA controls the formation of RNA, ribosomal RNA is the site of protein formations, transfer RNA carries specific AA to the ribosome to interact with mRNA, mRNA determines the sequence of AA

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15
Q

Where are proteins synthesized?

A

ribosomes (rRNA)

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16
Q

What carries the AA to the ribosomes?

A

tRNA

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17
Q

What determines the sequence of AA, determining what proteins are made and their quantity?

A

mRNA

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18
Q

Deamination involves the _______ of the amino group from the carbon skeleton; entrance of the amino group into the ________

A

removal; urea cycle

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19
Q

Transamination involves the _______ of the amino group from one AA to the carbon skeleton of a keto acid

20
Q

The ability of animal tissues to synthesize amino acids from other compounds as the basis for their clarification as _________ or _______________

A

essential; nonessential

21
Q

Conditionally essential amino acids

A

Amino acids that can become essential in certain physiologic conditions
ex. taurine in cats, proline in young pigs, tyrosine in people with PKU

22
Q

What are the differences between amino acids and imino acids?

A

Amino: building block of proteins, single bond, carboxylic, amine group, R group, hydrogen, ex. lysine
Imino: contains imino and carboxylic group together, double bond, ex. proline

23
Q

Is cysteine considered essential?

A

No, if the body has sulfur, it can make cysteine

24
Q

Methionine supplies methyl groups for _______
Choline is a precursor of ________ _________ and ________

A

creatine; homocysteine, cystine, ad cysteine

25
Is methionine considered essential?
yes, animals cannot synthesize it
26
Where the urea cycle take place?
partly in the mitochondria and cytoplasm
27
What is the main route of nitrogen excretion in birds?
uric acid
28
What is the difference between urea and uric acid excretion?
Urea: product of amino acid catabolism (breaking down AAs), plasma concentration reflects the amount or protein in diet, enters renal tubules through glomerular filtration, 50% reabsorbed, rest is excreted Uric acid: product of nucleic acid metabolism, enters renal tubules through glomerular filtration, 100% reabsorbed, 1-% secreted and excreted
29
Urea is excreted in the ______ and is the chief route of _________ excretion in __________
urine; nitrogen, mammals
30
T/F: there is no evidence of a metabolic requirement for dietary protein, but there is for amino acids
True
31
______ omnivores require specific dietary amino acids (essential amino acids) whereas ___________ herbivores are able to utilize nonprotein nitrogen for microbial amino acid synthesis in the lower part of the Gi tract
nonruminant; nonruminant
32
Adult _______ can depend entirely on nonprotein nitrogen in the diet by virtue of rumen microbes
ruminants
33
What is the most common of all nutrient deficiencies? Why?
N or amino acids, most energy sources are low in protein and protein supplements are expensive
34
What are some deficiencies of essential amino acids?
anorexia, reduced growth rate, reduced or negative N balance, reduced efficiency of feed utilization, reduced serum protein concentration, reduced birth weight of young, anemia, fat accumulation in the liver, edema, reduced milk production, reduced synthesis of certain enzymes and hormones
35
Tryptophan deficiency=
cataracts
36
threonine or methionine deficiency=`
fatty liver
37
lysine defciency in birds=
abnormal feathering
38
taurine deficiency in cats=
cardiomyopathy
39
glycine and proline deficiency=
abnormal growth in chickens
40
amino acid antagonism
growth depression that can be overcome wit supplementation
41
amino acid toxicity
used when the adverse effect of an amino acid in excess cannot be overcome with supplementation of another amino acid
42
amino acid imbalance
any change in the proportion of dietary amino acids that has an adverse effect preventable by a relatively small amount of the most limiting amino acids
43
antagonism differs from imbalance in that the supplemented amino acids ________ to be limited
does not need
44
fecal analysis method
Measurement of free amino acids in the plasma of animals at intervals following a meal of the test protein that allows a means of estimating the availability of one or more amino acids
45
microbiological assay