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Hugh's MD2 Core Conditions and Presentations > Alzheimer Disease > Flashcards

Alzheimer Disease Flashcards

1
Q

How can AD present?

A

Dementia

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2
Q

What are some risk factors for AD?

A

Increasing age (deposition of amyloid)

Genetic - presenilin and amyloid precursor protein gene, Apoe4

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3
Q

What are the histopathological features in AD?

A

Neurofilbrillary tangles - loss of normal cytoskeleton

Amyloid deposition (beta4 protein stain on autopsy)

  • Plaques
  • Vascular amyloid
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Hugh's MD2 Core Conditions and Presentations (67 decks)

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