Alz prev Flashcards
1
Q
Most common dementias
A
Alz and vascular dementia
2
Q
Prev
A
Memory impairment most common symptom
1 in 9 elderly above 65 diagnosed, prev around 5% little lower in NL
3 for men 7 for woman
3
Q
risk factor
A
Age Female Genetics (inherited is rare, 1-5%, caused by MUTATION in APP or and PS1&2. before 50) Cadiovascular risk factors Brain injury Inactive lifestyle Lower level of education Down syndrome (early age, 10-20 years younger)
4
Q
Three stages
A
Syndrome diagnosis
Specific diagnosis
Definite diagnosis (after death)
5
Q
Possible classification of AD
A
Probable AD; neurocognitive presentation, gradual onset and worsening
Prob AD with increased certainty; documented cog decline and genetic mutation
Possible AD ; atypical course or mixed presentation
Prob or possible AD with evidence of proces; extra: biomarker like dopamine, atrophy, cerebral spine fluid or PET scan)
6
Q
Stages
A
Asymptomatic; Preclinical
Symptomatic; MCI to advanced AD
7
Q
Stages
A
Asymptomatic; Preclinical
Symptomatic; MCI to advanced AD
