Agents used in Anemias and Hematopoetic Growth Factor

Question 1

Oral iron preparation with highest content

Answer 1

Fe carbonate

Question 2

Treatment for acute iron intoxication

Answer 2

Deferoxamine

Question 3

Triad of Hemochromatosis

Answer 3

Cirrhosis, DM, Skin pigmentation

Question 4

Role of vit B12

Answer 4

cofactor in transfer of 1C units

Question 5

What are he neurologic manifestations of vit B 12 deficiency?

Answer 5

ataxic gait, impaired position and vibratory sense, spasticity

Question 6

2 reactions where vit B 12 is essential

Answer 6

1. conversion of methylmalonyl coA to succinyl coA

2. conversion of homocysteine to methionine

Question 7

Myeloid GF that accelerates neutrophil recovery and reduces incidence of infections

Answer 7

Filgrastim (G-CSF)

Question 8

Megakaryocyte GF which activated IL-11 receptors

Answer 8

Oprelvekin