Ageing

Question 1

Negative interaction (non-drug) with statin

Answer 1

Grapefruit juice

Question 2

Negative interaction with metronidazole

Answer 2

Alcohol

Question 3

Negative interaction with warfarin

Answer 3

Cranberry

Question 4

Negative interaction (drug) with statin

Answer 4

Clarithromycin

Question 5

Result of using calcium and thyroxine together

Answer 5

Decreased absorption from GI tract

Question 6

Risk with NSAID and ACE-i together

Answer 6

Bleeding risk

Question 7

Risk with ACE-i and Spironolactone

Answer 7

Hyperkalaemia

Question 8

Digoxin and what drug precipitates digoxin toxicity

Answer 8

Verapamil

Question 9

Drugs which together cause serotonin syndrome

= hyperthermia, tremor

Answer 9

Fluoxetine + phenelzine

Question 10

B1 deficiency

• Signs
• Complication

Answer 10

= Wernicke’s encephalopathy
Signs: ophthalmoplegia, ataxia, confusion
- Can lead to irreversible Korsakoff’s syndrome

Question 11

Contraindications for Triptans

Answer 11

IHD
Uncontrolled hypertension
Concurrent use of lithium, SSRI or cabergoline