Acute Bacterial Meningitis

Question 1

Inflammation of meninges of brain and spinal cord

Answer 1

Acute Bacterial Meningitis

Question 2

3 bacteria account for 80% of cases

Answer 2

Etiology of Acute Bacterial Meningitis

Question 3

Bacteria reach meninges by blood, extension from nearby infected structures, and communication of CSF with exterior — Accumulation of exudate damages cranial nerves, induces thrombophiebitis leading to ischemia —- Damaged cell membranes disrupt blood-brain barrier causing brain edema —- Intracranial pressure rise, BP drops (septic shock) and death can occur

Answer 3

Pathophysiology of Acute Bacterial Meningitis

Question 4

Unexplained fever in infants 3mo-2y warrants lumbar puncture, Culture CSF sample

Answer 4

Diagnosis of Acute Bacterial Meningitis

Question 5

Abrupt neck flexion with patient in supine position results in involuntary flexion of hips and knees

Answer 5

Brudzinski’s sign

Question 6

Antibiotics, supportive for fever and dehydraion

Answer 6

Treatment for Acute Bacterial Meningiti