Abdominal Pharmacology Flashcards
What is the action of antacids?
Directly neutralise gastric acidity and inactivate pepsin
What is the action of anticholinergics?
Substances that block the action of neurotransmitter at synapses in the central and peripheral nervous system
What is the actions of sucralfate?
Forms a barrier to protect the mucosa from acid, pepsin and ulcers
What are the actions of PPI?
Irreversible inhibition of proton pump, preventing “pumping” or release of gastric acid
What are the actions of H2 receptors?
Reduce the amount of acid the stomach produces by lowering histamine production
What chemical messenger triggers release of prostaglandin?
Pyrogens
What following symptoms are red flag in patients with abdominal pain?
Weight loss
Anaemia
Silent interval in pain
Melana
Sporadic vomiting
Flatulence
Weight loss
Anaemia
Silent interval in pain
A mother is worried about her 4-month-old baby who has been unwell for two days, even though she cannot say exactly what she thinks is wrong. On examination his respiratory rate is 66 breaths per minute and his temperature is 38.3ºC. What is your working diagnosis for this patient?
Pneumonia
You are called to a 59 year old male who has been experiencing problems when urinating such as a difficulty in starting but an increased need to urinate. He has dialled 999 as he developed 10/10 pain after ejaculation, although this has improved greatly since the 999 call.
What is a possible working diagnosis for this patient?
Prostatitis
You are called by the partner of a 25-year-old man. They are concerned that since his return from Nepal 12 days ago he has had a high fever and one episode of watery diarrhoea that lasted 24 hours and subsided without treatment. Today he has started to feel feverish with a dull frontal headache and anorexia. His temperature rose to 39.4°C (103°F) and his headache and general fatigue worsened. He has also developed a dry cough and abdominal pain.
What do you think could be the cause of his symptoms?
Typhoid
What type of drug is omeprazole?
Protein pump inhibitor
What type of drug is omeprazole?
Protein pump inhibitor
Pupils hurt when you check with torch?
Meningitis
Aminosacilyate agents are used to treat IBD how do they work?
- Inhibit chemotactic response to leukotrine b4
- Draw water from rest of body into lumen
- Prevents leukocyte recruitment into bowel wall
- inhibits smooth muscle contraction in the GI tract
- diminishes the loss of fluid and electrolytes
Inhibit chemotactic response to leukotrine b4
Prevents leukocyte recruitment into bowel wall
What are the signs and symptoms of a LRTI?
productive cough, breathing difficulty, wheezes and crackles
