A.16 - Mycotoxicosis: human and animal poisonings of microfungi Flashcards

1
Q

Two thirds of fungi are…

A

Symbiotic

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2
Q

What are metabolites used for in fungi?

A
  • Protection from UV radiation
  • Attract hyphae of opposite sex
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3
Q

What can Terricolous fingi accumulate?

A
  • Pb
  • Cd
  • Hg
  • Insecticides
  • Herbicides
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4
Q

Give the most important mycotoxins

A
  • Aflatoxins
  • Ochratoxins
  • Fumonisins
  • Trichothecenes
  • Zearalenon
  • Rubratoxins
  • Ergot Alkaloids
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5
Q

What are Aflatoxins?

A
  • Mutagens, Immunosuppressants
  • Liver Damage
  • From Aspergillus species
  • Found on Fleshy Forages/Oil Plants
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6
Q

Ochratoxins

A
  • Nephrotoxins - Necrosis of renal tubules
  • Immunosuppresants, carcinogen
  • Aspergillus and Penicillium species
  • Found on Pork fat, coffee, Rye
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7
Q

Fumonisins

A
  • Leucoencephalomalacia in horses
  • Fumonisin B1 - Carcinogenic
  • Disrupts sphigolipid metabolism
  • Found on corn
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8
Q

Trichothecenes

A
  • Formed by Fusarium species
  • Nivalenol, Vomitoxin
  • Inhibit protein synthesis - affect ribosomes
  • Found on grasses and cereals
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9
Q

Zearalenon

A
  • Formed by Fusarium Species
  • Affects sexual maturation, enlarged genitals
  • Pigs particularly sensitive
  • Found on Grasses and Cereals
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10
Q

Rubratoxins

A
  • Produced by Penicillium and Aspergillus
  • Liver and Kidney Damage, CNS Affected
  • Found on Eggs, Dairy and Meat
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11
Q

Ergot Alkaloids

A
  • From Claviceps purpurea
  • or Fescue Toxicosis
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12
Q

Which toxins can affect animals when the host plant is consumed?

A

Phomopsins

Lolitrem B (Perennial rye grass)

Sporidesmin (Perennial rye grass)

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