A03 - Drugs for SZ Flashcards
What did Leuch et al study?
Meta analysis for 6000 patients and they put people on the drug and they put others on the placebo effect.
What were the results of Leuch’s study?
Those on a placebo within a year, 64% had a relapse, but only 24% on the drug have relapses.
What were the conclusions drawn from Leuch’s study?
therefore, significantly more effective than placebos.
What is the revolving door phenomenon?
Where you keep going back into hospital due to going back into the hospital constantly.
What are some of the less severe side effects of the drugs?
drowsiness, changes in weight, and visual disturbances.
What are some of the more severe side effects of this drug?
Depression, extrapyramidal side effects - 50% of patients on drugs develop parkisons disease.