8.9 Small for Gestational Age Flashcards

1
Q

Define small for gestational age (SGA) and how it is assed?

A

below 10th centile for gestational age.

Two measurements on US:

  • estimated fetal weight (EFW)
  • fetal abdominal circumference (AC)

Customised growth charts based on mothers:
weight; height; parity; ethnic group

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2
Q

When is it severe SGA?

A

when foetus is below 3rd centile for their GA

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3
Q

What weight is defined as “low birth weight”?

A

weight of less than 2500g

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4
Q

Two categories of SGA?

A
  • constitutionally small (small mother and family so is appropriate)
  • fetal growth restriction (FGR) aka intrauterine growth restriction (IUGR)
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5
Q

What is the difference between SGA and FGR?

A

SGA is small

FGR is when there is SGA due to a pathology limiting nutrients and O2

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6
Q

What two categories of causes of FGR are there?

A
  • placenta mediated growth restriction

- non-placenta mediated growth restriction (genetic or structural)

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7
Q

8 causes of placental mediated FGR / IUGR?

A
  • pre-eclampsia
  • maternal smoking
  • maternal alcohol
  • anaemia
  • malnutrition
  • infection
  • maternal health conditions
  • idiopathic (unknown)

(transfer of nutrients across placenta is affected)

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8
Q

4 causes of non-placenta mediated FGR?

A
  • genetic abnormalities
  • structural abnormalities
  • fetal infection
  • errors in metabolism
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9
Q

Other than SGA what other sign of FGR might there be?

A
  • reduced amniotic fluid volume
  • abnormal doppler
  • reduced fetal movements
  • abnormal CTGs
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10
Q

Short term complications of FGR?

A
  • fetal death or stillbirth
  • birth asphyxia
  • neonatal hypothermia
  • neonatal hypoglycaemia
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11
Q

Longterm complications of FGR?

A
  • cardiovascular disease esp hypertension
  • T2DM
  • obesity
  • mood and behaviour problems
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12
Q

Risk factors for FGR?

A
  • previous SGA baby
  • obesity
  • smoking
  • diabetes
  • HTN
  • pre-eclampsia
  • over 35 yrs
  • multiple pregnancy
  • low PAPPA
  • antepartum haemorrhage
  • antiphospholipid syndrome

(minor and major ones according to RCOG)

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13
Q

What does RCOG recommend for women at low risk fo FGR?

A

Measure symphysis fundal height (SFH) at every antenatal appointment from 24 weeks to identify potential SGA.
(plot on customised chart)

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14
Q

When would women be booked for serial growth scan with umbilical artery doppler?

A
  • SFH is <10th centile
  • three or more minor risk factors
  • one or more major risk factor
  • issues measuring SFH eg BMI or fibroids

(check RCOG green top guidelines for minor and major risk factors)

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15
Q

So the high risk of FGR or SGA indicates serial growth scan with umbilical artery doppler, what does this measure?

A
  • estimated fetal weight (EFW) and abdo circumference (AC)
  • umbilical artery pulsatility index UA-PI
  • amniotic fluid volume

(frequency etc of scan vary on local guidelines)

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16
Q

What do you do to investigate cause once a fetus is identified as SGA?

A
  • BP and urine dipstick for pre-eclampsia
  • uterine artery doppler scanning
  • detailed fetal anatomy scan by fetal medicine
  • karyotyping for chromosomal abnormalities
  • testing for infection (toxoplasmosis, CMV, syphilis, malaria)
17
Q

What steps can manage SGA?

A
  • identify those at risk
  • give aspirin in pre-eclampsia
  • treat modifiable risk factors eg smoking
  • serial growth scans
  • early delivery where growth is static