7.6 MICROBIAL INTERFERENCE AND SURFACE VIRULENCE TABLE Flashcards

1
Q

Type of Interference - Streptococci

A

Kill Phagocyte
Inhibit Chemotaxis
Resist phagocytosis
Resist digestion

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2
Q

Kill phagocyte (Streptococci)

A

Streptolysin induces lysosomal discharge into cell cytoplasm

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3
Q

Inhibit chemotaxis (Streptococci)

A

Streptolysin

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4
Q

Resist phagocytosis (Streptococci)

A

M substance

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5
Q

Type of Interference - Staphylocci

A

Kill phagocyte
Inhibit opsonization
Resist killing

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6
Q

Kill phagocyte (Staphylococci)

A

Leukocidin induces lysosomal discharge into cell cytoplasm

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7
Q

Inhibit opsonization (Staphylococci)

A

Protein A blocks Fc portion of Ab

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8
Q

Resist killing (Staphylococci)

A

Cell wall mucopeptide

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9
Q

Bacillus anthracis - Type of Interference

A

Kill phagocyte
Resist killing

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10
Q

Kill phagocyte (Bacillus anthracis)

A

Toxic complex

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11
Q

Resist Killing (Bacillus anthracis)

A

Capsular polyglutamic acid

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12
Q

Resist phagocytosis (unless Ab present) (Haemophilus influenzae)

A

Polysaccharide capsule

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13
Q

Resist phagocytosis (unless Ab present) - Pseudomonas aeruginosa

A

“Surface slime” (polysaccharide)

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14
Q

Klebsiella pneumoniae - Type of Interference

A

Resist Digestion

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15
Q

Resist phagocytosis (unless Ab present) - E. coli

A

O antigen (smooth strains) and K antigen (acid polysaccharide)

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16
Q

Resist killing (E. coli)

A

K antigen

17
Q

Resist phagocytosis (unless Ab present) - Salmonella typhi

A

Vi antigen

18
Q

Resist phagocytosis (Cryptococcus neoformans)

A

Polysaccharide capsule

19
Q

Resist phagocytosis (Treponema pallidum)

A

Cell Wall

20
Q

Resist killing (Yersinia pestis)

A

Protein-carbohydrate cell wall

21
Q

Resist killing and digestion (Mycobacteria)

A

Cell Wall Structure

22
Q

Resist killing (Brucella abortus)

A

Cell wall substance

23
Q

Streptococcus pneumonia - Virulence Factor and Used in Vaccine (Yes/No)

A

Polysaccharide capsule - YES

24
Q

Streptococcus pyogenes - Virulence Factor and Used in Vaccine (Yes/No)

A

M protein - NO

25
Q

Staphylococcus aureus - Virulence Factor and Used in Vaccine (Yes/No)

A

Protein A - NO

26
Q

Neisseria meningitides - Virulence Factor and Used in Vaccine (Yes/No)

A

Polysaccharide capsule - YES

27
Q

Bacillus anthracis - Virulence Factor and Used in Vaccine (Yes/No)

A

Polypeptide capsule - NO

28
Q

Haemophilus influenzae - Virulence Factor and Used in Vaccine (Yes/No)

A

Polysaccharide capsule - YES

29
Q

Klebsiella pneumoniae - Virulence Factor and Used in Vaccine (Yes/No)

A

Polysaccharide capsule - NO

30
Q

Escherichia coli - Virulence Factor and Used in Vaccine (Yes/No)

A

Protein pili -NO

31
Q

Salmonella typhi - Virulence Factor and Used in Vaccine (Yes/No)

A

Polysaccharide capsule - NO

32
Q

Yersinia pestis -Virulence Factor and Used in Vaccine (Yes/No)

A

V and W proteins - NO