7.5 chromosomal abnormalities Flashcards
What is nondisjunction?
When chromosomes do not separate properly.
How can nondisjunction happen in meiosis l?
Homologous chromosomes do not separate
How can nondisjunction affect cells?
Cells can have no chromosomes or too many
What is x-chromosome inactivation?
When each cell randomly inactivates one x-chromosome which becomes an inactive bar body which shrivels up and becomes silent
Why are humans more tolerant of extra sex chromosomes?
y chromosomes are not essential to human life and extra x chromosomes get deactivated by x chroosome inactivation.
What are autosomes?
chromosomes #1-22
What are other chromosome abnormalities?
deletion, duplication, inversion, translocation
How is sex determined?
If you get a y chromosome
What is the result of deletion?
Missing genes