7.3 Pyruvate Oxidation

Question 1

glycolysis occurs in almost all living organisms but it does not:

Answer 1

generate very much energy in the form of ATP, pyruvate still contains lots of chemical potential energy in its bonds

Question 2

in the presence of oxygen, pyruvate can be further:

Answer 2

oxidized to release more energy, first to acetyl-CoA and then even further in the citric acid cycle

Question 3

in eukaryotes, pyruvate oxidation is the first step that takes place in the:

Answer 3

mitochondria

Question 4

the end products of glycolysis (pyruvate) are transported into the:

Answer 4

mitochondria

Question 5

intermembrane space

Answer 5

the space between the inner and outer mitochondrial membranes

Question 6

mitochondrial matrix

Answer 6

the space enclosed by the inner membrane of the mitochondria

Question 7

pyruvate is first transported into the:

Answer 7

mitochondrial matrix where it is converted into acetyl-CoA

Question 8

how is pyruvate converted into acetyl CoA?

Answer 8

part of the pyruvate molecule is oxidized and splits off to form CO2, the electrons lost in this process are donated to NAD+ to form NADH, the remaining part of the pyruvate is an acetyl group which contains large amounts of potential energy and is transferred to (CoA)

Question 9

carbon dioxide is the most oxidized and _____

Answer 9

least energetic form of carbon

Question 10

what is the first substrate in the citric acid cycle?

Answer 10

acetyl-CoA

Question 11

the synthesis of one molecule of acetyl-CoA from pyruvate results in the:

Answer 11

formation of one molecule of carbon dioxide and one molecule of NADH

Question 12

what is produced in the pyruvate oxidation stage from a single starting molecule of glucose?

Answer 12

two molecules of carbon dioxide, two molecules of NADH, and two molecules of acetyl-CoA