72. monocytes Flashcards
1
Q
What type of cells are monocytes
A
large, phagocytic leukocyte cells
agranulocyte
2
Q
what are monocytes precursor to
A
macrophages, osteoclasts, microglia etc
3
Q
how do you spot monocyte down the microscope
A
*largest cell
- bluish grey in colour due to lysosomes/azurophillic granules
- bean/horseshoe shaped nucleus
4
Q
What is the chromatin like in monocytes
A
less condensed that lymphocytes
5
Q
How are monocytes important in immune defence
A
they are all antigen presenting cells
6
Q
How do monocytes develop and by which process
What happens after they mature
A
Monocytopoiesis
from the bone marrow from MONOBLAST CELLS
monoblasts mature to become monocytes, they circulate blood, then penetrate CONNECTIVE TISSUE
They further mature and acquire PHAGOCYTIC PROPERTIES
7
Q
What are the three main functions of monocytes
A
phagocytosis
antigen presentation
cytokine production
