22. lysosomes and endosomes Flashcards
1
Q
What are lysosomes responsible for
A
intracellular digestion abundant in cells with phagocytic activity like macrophages
2
Q
What do lysosomes contain
A
hydrolytic enzymes synthesised in RER
Membrane receptors for M6P-proteins then ensure correct packaging in the Golgi apparatus in small vesicles called endosomes, creating lysosomes.
They operate at ph 4.5
3
Q
What controls synthesis of lysosomes
A
nuclear genes
4
Q
What happens after a lysosome has broken down waste material
A
fuse with autophagy (self-eating)
vacuoles and effectively destroy itself
5
Q
what happens if lysosome enzymes leak into cell
A
work at ph 5
cytosol ph 7.2
