7-Lymph, Integumentary, GI, Endocrine Flashcards
What are the functions of the Lymphatic system (2)
- Remove waste products from cells
- Manage infections
What is the role of lymph fluid
Wash away waste from the normal function of cells
How does lymph work (4)
- Bathes all cells of the body
- Cleanses tissues
- Moves through lymphatic vessels, to lymph noes and organs
- Rejoins general circulation
Location of the bodies lymph noes
Clusters in the groin, armpits, neck, intestines
What is inside lymph nodes and its roles (3)
-Lymphocytes (WBC)
- Produce antibodies
- Phagocytosis of infectious microorganisms
- Create recognition for that infection and destroy it
What are 3 lines of defense in the immune system
- Skin
- Inflammatory response (Primary response)
- Immunity (Secondary response
Define allergen
Antigen causing allergic reaction
Define antibodies
Attack specific antigens
Define immunoglobulins (IG)
Proteins acting as antibodies
Explain the primary response (2)
- Cells attract, identify, search for and surround invader
- Antibodies are then produced in case it enters again
What are basophils
Guard specific sites
What are mast cells
Cells that roam the body for invading microorganisms
What mediators do basophils and mast cells produce (5)
- Histamine
- Eosinophil
- Arachidonic acid
- Protoglycans
- Kinins
What happens if an “intruder” returns to the body (3)
- Antibodies release the mediators
- More WBC are called to defend
- More blood is called in
- Vasodilation
- Capillary permeablility
What are the effects of histamine (3)
- Increase vascular permeability
- Reduces BP
- Reduced vessel volume
- Reduced preload
- Urticaria (hives)
- Capillary and venous dilation
- Rapid onset, short duration
What are the effects of leukotrienes
- Coronary vasoconstriction
- Wheezing
- Slow acting, long duration
Effects of eosinophils, heparin, kinins, prostoglandins, thromboxanes (3)
- Fever, chills
- Bronchospasm
- Pulmonary vasonconstriction
What is angioedema
Swelling of tongue, face and lips
What are the 2 types of lymphocytes
- B
- T
What are b lymphocytes and an example
- Produced by bone marrow and mature in the bone, attack specific organism
- Antibodies (Humoral)
What are t lymphocytes and an example
- Produced by bone marrow and mature in thymus, not specific/attack all foreign organisms. The do not produce antibodies
- White Blood Cells
What is acquired immunity
- Vaccine produces antibodies
- Dont get the disease
- Rides the disease if it invades
What is natural immunity
- Get a disease
- Antibodies are produced
- Acquire symptoms of the disease
What is an antibody (3)
- Developed in a controlled manner
- Produced by B lymphocytes (attack specific antigen)
- Binds with antigen to remove or manipulate it
What is an immunoglobulin
-Proteins that act as antibodies
What are the classes of immunoglobulins and their roles
- IgM- Produced first
- IgG- Has “memory”
- IgA- Involved in secretory immune response
- IgE- Involved in allergic reactions
- IgD- Present in very low concentrations
What is the most important immunoglobulin to know and why
- IgE
- Its involved in allergic reactions
What type of attack is anaphylaxis considered
Systemic attack
Difference between immune and inflammatory response
- Inflammation is faster
- Immune targets specific antigens
- Inflammations involves many types of WBC and platelets
- Inflammation involves several plasma proteins
What is the largest organ of the body
Skin