7 Cell Cycle and Cell Checkpoints Flashcards
For cell growth. By the end of this a cell has two full sets of DNA (chromosomes) and is large enough to begin the division process.
Interphase
for cell division: making two cells out of one.
M- phase
quiescence (state/senescent state),
Resting phase
Gap 0
cell that do no divide anymore (nerve cell)
Permanent cell
cells that divide when needed
Stable cell
cell that always divide
Labile cell
Chromosomes condense and are more visible.
The nuclear membrane (envelope) disappears.
Prophase
Centrioles have separated and taken positions on the opposite poles of the cell. Spindle fibers form and radiate toward the center of the cell.
Prophase
Chromosomes line up across the middle of the cell. Spindle fibers connect the centromere of each sister chromatid to the poles of the cell.
Metaphase
Centromeres that join the sister chromatids split,
Sister chromatids separate becoming individual chromosomes and will move to opposite poles of the cell.
Anaphase
Chromosomes (each consisting of a single chromatid) uncoil. Spindle fibers break down and dissolve. Then Cytokinesis begins.
Telophase
division of the cytoplasm into two individual cells.
Cytokinesis
In synthesis phase, DSBs cause deletions, translocations, and fusions in the DNA. What does DSB refers to?
Double stranded breaks
In gap 2, in order to repair DSB ________ should recognize the damage
Endonuclease