7-1 (8.12.16) Flashcards
most of the time a cell’s membrane potential is (+/-)
negative
things that influence whether an ion will flow thru membrane
1) [ ] gradient
2) electrical gradient
3) permeability of membrane for ion
define inward current
flow of positive charge INTO cell
define Nernest equilibrium
voltage gradient exactly compensates the concentration gradient, so NO NET flux
purpose of Nernest eq
what other thing does the same thing
predict if ion will have net flux in or out of cell at a given membrane potential
net driving force (Vm - Eion)
define the eq components of net driving force
Vm is membrane potential
Eion is Nernst potential
resting membrane potential is near E_?
k
near potassium’s
define reversal potential
when there’s no net ionic flux thru channel
purpose of knowing reversal potential
predict whether opening/closing of ion channel will depolarize or hyperpolarize membrane
GHK eq - how it’s gonna be tested
know that it calculates Vm (membrane potential)
know that you plug in permeability and [ ] gradient
eq predicts reversal potentials
define epithelium
cellular covering of internal and external surfaces of body,
features of epithelial tissue
- arranged in what
- rests on what
- derived from what
- vascular or avascular
- arranged in sheets
- rests on basal lamina
- derived from all three germ layers
- avascular
cells exhibit “” (polarity)
what does this mean
sidedness
all surfaces are NOT equal
dif bt apical and lateral and basal surface
apical interacts with lumen (read: refers to TOP, like apex)
lateral HAS intercellular junctions (read: refers to internal stuff)
basal interacts with underlying connective tissue (refers to bottom)
stereo cilia is most closely related to what
micro villi