12-1 (8.19.16) Flashcards
defective neural tube fusion happens at wk #
3
name neural tube defects (3)
1) an-en-ce-phaly
2) en-ce-phalo-cele
3) spina bifida
how do you screen for neural tube defects
screen for UP alpha-fetoprotein (AFP)
in
maternal serum and amniotic fluid
how do you prevent neural tube defects
give mom folic acid
”” cells are the predominant neuron in cortex
pyramidal
cerebrum vs cereBELLUM: which has more layers of cortical gray matter
BRUM
which of the neuron cells looks literally like a bush
which neuron looks like a triangle
Purkinje
triangle - pyramidal
match to correct term
- bodies
- gray matter
- process
- white matter
gray + body
process + white
define Nissl substance
RER that make peptide NT
axons are like tracks…what is its main protein
microtub
anterograde
retrograde
protein involved in each
A = kinesin R = dynein
glial cell MAIN idea purpose
support and protect neurons
glial cell: neurons
ratio of #
G: N
10:1
these two form myelin
- Schwann
- ??
match them to CNS or PNS
?? = oligo-dendro-cyte (CNS)
PNS for other
what does an oligo-dendro-cyte look like
like a rounded OLIVE
what is gyri and sulci
the folds of the cerebral cortex surface
read: gray matter consists of cell bodies (unm) and rest
white matter: JUST axons
-
how many layers of cortex
6
pyramidal cell function
transmit signal to other parts of CNS
main physio problem of multiple sclerosis
immune system attacks myelin
name the layers of the meninges
pia
arachnoid
dura
which organ produces CSF
choroid plexus
define the meninges
system of membranes that envelops the CNS
arachnoid
-consists of
pia mater
-consists of
stack the three layers
A
-CSF
P
-collagen
DURA
A
P
function of ependymal cell
creates CSF
weird fact about cell bodies
autonomic ganglia is found in PNS/CNS
NONE in nerves
only in CNS or ganglia
AG - PNS
electrical synapses consist of electrical connections thru what
ion channels in gap junctions
chemical synapses release “” to ensue with its function
chem NT
list out the steps of a chem synapse in neuromuscular junction
1) AP arrives; dep happens
2) Ca channels open
3) vesicles release ACh into cleft; ACh opens ion channels; dep to threshold
local dep is called
endplate potential
dif bt muscle and posts nerve cell
hint: decide to fire AP
posts has to integrate many inputs from various sources in order to decide whether to fire an action potential
which dep result from opening of NONselective cation channels
EPSP
most common inhibitory NT in brain
GABA
EPSP reversal potential =
IPSP “”
EP = 0
IP = near Nernest eq for K or Cl
excitation of flexor motorneuron is accompanied by…so that the leg bends
inhibition of extensor motorneuron
EPSP mec
IPSP mec
E
-opening of nonselective cation channels (Na and K)
I
-opening of selective channels (K or Cl)
AA that generate EPSP
IPSP
glutamate, aspartate
I = GABA
define saltatory conduction
when AP jump from node to node