(6.2) Receptor Secondary Messenger and Location Flashcards

1
Q

α1A secondary messenger

A

Gq

increase IP3/DAG

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2
Q

α1B secondary messenger

A

Gq

increase IP3/DAG

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3
Q

α1D secondary messenger

A

Gq

increase IP3/DAG

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4
Q

α2 A secondary messenger

A

Gi

Decrease cAMP

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5
Q

α2B secondary messenger

A

Gi

Decrease cAMP

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6
Q

α2C secondary messenger

A

Gi

Decrease cAMP

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7
Q

β1 secondary messenger

A

Gs

Increase cAMP

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8
Q

β2 secondary messenger

A

Gs

Increase cAMP

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9
Q

β3 secondary messenger

A

Gs

Increase cAMP

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10
Q

D1 secondary messenger

A

Gs

Increase cAMP

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11
Q

D2 secondary messenger

A

Gi

Decrease cAMP

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12
Q

D3 secondary messenger

A

Gi

Decrease cAMP

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13
Q

D4 secondary messenger

A

Gi

Decrease cAMP

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14
Q

D5 secondary messenger

A

Gs

Increase cAMP

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15
Q

M1 secondary messenger

A

Gq

increase IP3/DAG

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16
Q

M2 secondary messenger

A

Gi

Decrease cAMP

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17
Q

M3 secondary messenger

A

Gq

increase IP3/DAG

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18
Q

M4 secondary messenger

A

Gi

Decrease cAMP

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19
Q

M5 secondary messenger

A

Gq

increase IP3/DAG

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20
Q

NM secondary messenger

A

α2β

Na/K channel for depolarization

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21
Q

NN secondary messenger

A

α/β only

Na/K channel for Depolarization

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22
Q

Easy way to remember M receptors

A

Odds are Gq

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23
Q

Easy way to remember D receptors

A

D1 and D5 are increase cAMP

all others decrease cAMP

24
Q

What Muscarinic receptor predominates the heart

25
What muscarinic receptor primarily found in smooth muscle
M3 and M2
26
most common muscarinic receptor in most organs
M3 | or otherwise about equal
27
Adrenergic receptor for relaxation of ciliary muscle for far vision
β2
28
adrenergic receptor for lacrimal secretions
α
29
adrenergic receptor for radial muscle contraction in eye
α1
30
adrenergic receptor to increase SA activity
β1>β2
31
adrenergic receptor to increase contractility and conduction speed
β1>β2
32
adrenergic receptor to increase AV activity
β1>β2
33
adrenergic receptor to increase his-purkinje system activity
β1>β2
34
adrenergic receptor to increase ventricular contractility and conduction velocity
β1>β2
35
adrenergic receptor for vasoconstriction
α1
36
adrenergic receptor for bronchodilation
β2
37
adrenergic receptor for pregnant uterine contraction
α1
38
adrenergic receptor for pregnant uterine relaxation
β2
39
adrenergic receptor for nonpregnant uterine relaxation
β2
40
adrenergic receptor for pilomotor contraction
α1
41
adrenergic receptor for localized skin secretions
α1
42
adrenergic receptor to increase salivary gland secretion
α1
43
adrenergic receptor to increase skeletal muscle contractility
β2
44
Eye muscarinic receptor
M3, M2
45
Muscarinic Receptor to slow SA node
M2>>M3
46
Muscarinic Receptor to decrease contractility and conduction velocity in atria
M2>>M3
47
Muscarinic Receptor to decrease AV conduction velocity
M2>>M3
48
Muscarinic Receptor receptor to decrease activity of His-Purkinje system
M2>>M3 not very effective
49
Muscarinic Receptor in blood vessel and arteries to vasodilate
this isn't a thing :)
50
Muscarinic Receptor in endothelium to activate NO system
M3
51
Muscarinic Receptor for tracheal/bronchial constriction
M2=M3
52
Muscarinic Receptor to increase bronchial gland stimulation
M3, M2
53
M1 are generally found
in nerves
54
M2 are generally found
heart nerves smooth muscle
55
M3 are generally found
glands smooth muscle endothelium
56
M4 are generally found
CNS
57
M5 are generally found
CNS