(22.1) Anti-fungal, Anti-influenza and Anti-TB Pharm (Sheehy)

Question 1

Answer 1

D. Fluconazole

Question 2

Answer 2

E. Minor upset GI symptoms

Question 3

What is the “take home point” for drugs ending in -azole?

Answer 3

WELL TOLERATED

The best tolerated of all the anti-fungals

Question 4

Answer 4

D. Voriconazole

Question 5

Answer 5

C. Voriconazole

Question 6

Answer 6

C. Lipid formulation

Question 7

What is ergosterol?

Answer 7

Vital part of the cell membranes of fungi

Not found in the cell membranes of humans

Question 8

State the antifungal drug that inhibits:

Membrane function

Answer 8

Amphotericin B

Question 9

State the antifungal drug that inhibits:

Cell wall synthesis

Answer 9

Echinocandins

Caspofungin, Micafungin, Anidulafungin

Question 10

State the antifungal drug that inhibits:

Ergosterol synthesis

Answer 10

Fluconazole

Itraconazole

Voriconazole

Question 11

State the antifungal drug that inhibits:

Nucleic acid synthesis

Answer 11

Flucytosine

Question 12

Answer 12

A. Oseltamivir

Or

C. Peramivir

Question 13

Answer 13

C. Ethambutol

Question 14

Answer 14

B. Inhibition of mycobacterial arabinosyl transferases

Question 15

Answer 15

D. Increase the dose of warfarin

Question 16

Answer 16

D. Streptomycin and moxifloxacin